SCHEMBL9816154

SCHEMBL9816154

CN(C)c1cccc2cc(O)ccc12

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 1/20 0.73
KDM4E B2RXH2 1/20 0.47
GAA P10253 1/20 0.47
MAPT P10636 1/20 0.47
TLR8 Q9NR97 1/20 0.45
ALDH1A1 P00352 1/20 0.44
TSHR P16473 1/20 0.44
CYP1A2 P05177 2/20 0.43
SIGMAR1 Q99720 1/20 0.43
ESR1 P03372 6/20 0.42
ESR2 Q92731 6/20 0.42
HSD17B1 P14061 3/20 0.42
HSD17B2 P37059 3/20 0.42
EP300 Q09472 1/20 0.40
KAT2B Q92831 1/20 0.40
KAT8 Q9H7Z6 1/20 0.40
NQO2 P16083 1/20 0.39
IDH1 O75874 1/20 0.38
PTPN1 P18031 1/20 0.38
CYP3A4 P08684 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29349880 0.85 MCL1 (1.00) MCL1KDM4EGAAMAPTALDH1A1
SCHEMBL11817172 0.80 ALDH1A1 (0.49) MCL1KDM4EMAPTTLR8ALDH1A1
SCHEMBL25969102 0.79 GAA (0.59) MCL1GAAMAPTTLR8ALDH1A1
SCHEMBL2025062 0.78 MCL1 (0.50) MCL1KDM4EGAAMAPTALDH1A1
SCHEMBL14584326 0.78 CYP1A2 (0.59) MCL1KDM4EGAAMAPTALDH1A1
SCHEMBL14975317 0.78 NQO2 (0.55) MCL1KDM4EGAAMAPTALDH1A1
SCHEMBL5487330 0.77 MCL1 (0.62) MCL1KDM4EGAAMAPTALDH1A1
SCHEMBL17993263 0.77 MCL1 (0.49) MCL1KDM4EGAAMAPTALDH1A1
SCHEMBL17964122 0.77 MCL1 (0.49) MCL1KDM4EGAAMAPTALDH1A1
SCHEMBL29364795 0.74 SIGMAR1 (0.63) MCL1KDM4EGAAMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11919921-B2 Galactoside inhibitor of galectins GALECTO BIOTECH AB (DK) 2024-03-05 US disclosed
US-20220289783-A1 NOVEL GALACTOSIDE INHIBITOR OF GALECTINS GALECTO BIOTECH AB (DK) 2022-09-15 US disclosed
US-11377464-B2 Galactoside inhibitor of galectins GALECTO BIOTECH AB (DK) 2022-07-05 US disclosed
US-11377464-B2 Galactoside inhibitor of galectins GALECTO BIOTECH AB (DK) 2022-07-05 US disclosed
CN-113621005-A alpha-D-galactoside inhibitors of galectins 格莱克特生物技术公司 2021-11-09 CN disclosed
CN-107406478-B alpha-D-galactoside inhibitors of galectins 格莱克特生物技术公司 2021-07-27 CN disclosed
EP-3828191-A2 NOVEL GALACTOSIDE INHIBITOR OF GALECTINS Galecto Biotech AB (DK) 2021-06-02 EP disclosed
EP-3828191-A2 NOVEL GALACTOSIDE INHIBITOR OF GALECTINS Galecto Biotech AB (DK) 2021-06-02 EP disclosed
EP-3250581-B1 ALPHA-D-GALACTOSIDE INHIBITORS OF GALECTINS GALECTO BIOTECH AB (DK) 2021-01-20 EP disclosed
EP-3250581-B1 ALPHA-D-GALACTOSIDE INHIBITORS OF GALECTINS GALECTO BIOTECH AB (DK) 2021-01-20 EP disclosed
US-20170349619-A1 ALPHA-D-GALACTOSIDE INHIBITORS OF GALECTINS GALECTO BIOTECH AB (DK) 2017-12-07 US disclosed
US-20170349619-A1 ALPHA-D-GALACTOSIDE INHIBITORS OF GALECTINS GALECTO BIOTECH AB (DK) 2017-12-07 US disclosed
EP-3250581-A1 ALPHA-D-GALACTOSIDE INHIBITORS OF GALECTINS Galecto Biotech AB (DK) 2017-12-06 EP disclosed
CN-107406478-A ALPHA-D-GALACTOSIDE INHIBITORS OF GALECTINS 格莱克特生物技术公司 2017-11-28 CN disclosed
WO-2016120403-A1 ALPHA-D-GALACTOSIDE INHIBITORS OF GALECTINS GALECTO BIOTECH AB (DK) 2016-08-04 WO disclosed
WO-2016120403-A1 ALPHA-D-GALACTOSIDE INHIBITORS OF GALECTINS GALECTO BIOTECH AB (DK) 2016-08-04 WO disclosed
EP-0255643-B1 METAL COMPLEX COMPOUND USEFUL AS A NEAR INFRARED ABSORBER HODOGAYA CHEMICAL CO., LTD. (JP) 1991-10-09 EP disclosed
US-4977249-A FOR OPTICAL FILTERS OR SHIELDS HODOGAYA CHEMICAL CO., LTD. (JP) 1990-12-11 US disclosed
EP-0255643-A2 Metal complex compound useful as a near infrared absorber HODOGAYA CHEMICAL CO., LTD. (JP) 1988-02-10 EP disclosed
US-3930672-A Pressure-sensitive copying paper containing lactone compounds derived from pyridine-carboxylic acid HODOGAYA CHEMICAL CO., LTD. (JA) 1976-01-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11377464-B2 Galactoside inhibitor of galectins LGALS3, LGALS1, LGALS2 MCL1 1264/4885KDM4E 3155/4885GAA 102/4885
US-11919921-B2 Galactoside inhibitor of galectins LGALS3, LGALS1, LGALS2 MCL1 1264/4885KDM4E 3155/4885GAA 102/4885
US-20220289783-A1 NOVEL GALACTOSIDE INHIBITOR OF GALECTINS LGALS1, LGALS3, LGALS2 MCL1 1592/4885KDM4E 3342/4885GAA 96/4885
US-20170349619-A1 ALPHA-D-GALACTOSIDE INHIBITORS OF GALECTINS LGALS3, LGALS1, LGALS2 MCL1 998/4885KDM4E 3105/4885GAA 88/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.