SCHEMBL179933

SCHEMBL179933

Nc1cc(C(=O)CI)ccc1C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.46
KDM4E B2RXH2 8/20 0.46
HPGD P15428 3/20 0.46
HSD17B10 Q99714 3/20 0.46
TDP1 Q9NUW8 4/20 0.45
CYP3A4 P08684 3/20 0.45
ALOX15 P16050 1/20 0.45
GSK3B P49841 1/20 0.44
PPM1B O75688 1/20 0.44
MAPT P10636 6/20 0.42
GAA P10253 3/20 0.42
GLA P06280 2/20 0.42
CASP1 P29466 1/20 0.42
CASP7 P55210 1/20 0.42
ATM Q13315 1/20 0.42
IDO1 P14902 1/20 0.42
CDC25B P30305 2/20 0.41
CASP6 P55212 1/20 0.41
RCE1 Q9Y256 1/20 0.41
KMT2A Q03164 3/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29482064 1.00 ALDH1A1 (0.46) ALDH1A1KDM4EHPGDHSD17B10TDP1
SCHEMBL9509375 0.84 ALDH1A1 (0.47) ALDH1A1KDM4EHPGDHSD17B10TDP1
SCHEMBL29067063 0.83 KDM4E (0.53) ALDH1A1KDM4EHPGDHSD17B10TDP1
SCHEMBL29377257 0.81 KDM4E (0.55) ALDH1A1KDM4EHPGDHSD17B10TDP1
SCHEMBL30162845 0.81 KDM4E (0.55) ALDH1A1KDM4EHPGDHSD17B10TDP1
SCHEMBL143267 0.81 KDM4E (0.55) ALDH1A1KDM4EHPGDHSD17B10TDP1
SCHEMBL11455991 0.80 ALDH1A1 (0.52) ALDH1A1KDM4EHPGDHSD17B10TDP1
SCHEMBL27450524 0.79 ALDH1A1 (0.47) ALDH1A1KDM4EHPGDHSD17B10TDP1
SCHEMBL23357752 0.79 KDM4E (0.53) ALDH1A1KDM4EHPGDHSD17B10TDP1
SCHEMBL3939033 0.79 TDP1 (0.55) ALDH1A1KDM4EHPGDHSD17B10TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2213 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240239885-A1 ANTIBODY CONJUGATE COMPRISING ANTI-P-CADHERIN ANTIBODY AND USES THEREOF WuXi Biologics Ireland Limited (IE) 2024-07-18 US claimed
WO-2023195805-A9 ITGB2-MEDIATED DRUG DELIVERY SYSTEM 트윈피그바이오랩(주) 2024-07-11 WO claimed
CN-117940169-A Use of antibody drug conjugate and combined drug and use thereof 上海美雅珂生物技术有限责任公司 2024-04-26 CN claimed
US-11951173-B2 Tetravalent antibody-drug conjugates and use thereof Bliss Biopharmaceutical (Hangzhou) Co., Ltd. (CN) 2024-04-09 US claimed
WO-2024061305-A1 GPC3 ANTIBODY-DRUG CONJUGATE AND USE THEREOF 上海美雅珂生物技术有限责任公司 2024-03-28 WO claimed
WO-2024044550-A1 DLL3 BINDING MOLECULES AND USES THEREOF Abdera Therapeutics Inc. (US) 2024-02-29 WO claimed
CN-117616052-A Antibody drug conjugate and application thereof 江苏康宁杰瑞生物制药有限公司 2024-02-27 CN claimed
EP-4321526-A1 PEPTIDE LIGAND TARGETING CARBONIC ANHYDRASE IX, PEPTIDE CONSTRUCT COMPRISING SAME, AND USES THEREOF C-Biomex Co., Ltd. (KR) 2024-02-14 EP claimed
WO-2024023289-A1 B CELL-SPECIFIC MAB-SIRNA CONJUGATES IMPROVE MYASTHENIA ASSOCIATION FRANCAISE CONTRE LES MYOPATHIES (FR) 2024-02-01 WO claimed
EP-4311579-A1 B CELL-SPECIFIC MAB-SIRNA CONJUGATES IMPROVE MYASTHENIA Association Française contre les Myopathies (FR) 2024-01-31 EP claimed
EP-0196669-B1 IMPROVED METHOD OF CONJUGATING METALLOTHIONEIN TO BIOLOGICALLY ACTIVE MOLECULES THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1992-02-12 EP claimed
US-5077210-A Binding of proteins for use as biosensors, bioassays SCIENCE APPLICATIONS INTERNATIONAL CORPORATION 1991-12-31 US claimed
EP-0440647-A1 LABELED NUCLEIC ACID PROBE BIOGEN, INC. (US) 1991-08-14 EP claimed
EP-0366770-A1 LIPOSOMES COUPLED TO HORMONES. SANDOZ AG (CH) 1990-05-09 EP claimed
WO-1989012110-A1 LABELED NUCLEIC ACID PROBE BIOGEN, INC. (US) 1989-12-14 WO claimed
WO-1989011270-A1 LIPOSOMES COUPLED TO HORMONES SANDOZ AG (CH) 1989-11-30 WO claimed
EP-0298684-A2 Crosslinking reagents useful in treating hair UNILEVER PLC (GB) 1989-01-11 EP claimed
EP-0196669-A2 Improved method of conjugating metallothionein to biologically active molecules THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1986-10-08 EP claimed
US-4360592-A COUPLING REAGENTS FOR ENZYME CONJUGATES; IMMUNOASSAY WELTMAN JOEL K 1982-11-23 US claimed
US-4251445-A ENZYME CONJUGATES WELTMAN JOEL K 1981-02-17 US claimed