Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | PPM1B | O75688 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | GLA | P06280 | 2/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | CDC25B | P30305 | 2/20 | 0.42 |
| ▸ | CASP6 | P55212 | 1/20 | 0.42 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | GFER | P55789 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27450524 | 0.84 | ALDH1A1 (0.47) | ALDH1A1KDM4EHSD17B10HPGDTDP1 | |
| SCHEMBL29067063 | 0.84 | KDM4E (0.53) | ALDH1A1KDM4EHSD17B10HPGDTDP1 | |
| SCHEMBL179933 | 0.84 | ALDH1A1 (0.46) | ALDH1A1KDM4EHSD17B10HPGDTDP1 | |
| SCHEMBL29482064 | 0.84 | ALDH1A1 (0.46) | ALDH1A1KDM4EHSD17B10HPGDTDP1 | |
| SCHEMBL143267 | 0.82 | KDM4E (0.55) | ALDH1A1KDM4EHSD17B10HPGDTDP1 | |
| SCHEMBL30162845 | 0.82 | KDM4E (0.55) | ALDH1A1KDM4EHSD17B10HPGDTDP1 | |
| SCHEMBL29377257 | 0.82 | KDM4E (0.55) | ALDH1A1KDM4EHSD17B10HPGDTDP1 | |
| SCHEMBL23357752 | 0.80 | KDM4E (0.53) | ALDH1A1KDM4EHSD17B10HPGDTDP1 | |
| SCHEMBL3939033 | 0.80 | TDP1 (0.55) | ALDH1A1KDM4EHSD17B10HPGDTDP1 | |
| SCHEMBL31195371 | 0.80 | KDM4E (0.53) | ALDH1A1KDM4EHSD17B10HPGDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0317645-B1 | 4H-3,1-BENZOXAZIN-4-ONE COMPOUNDS AND SERINE PROTEASE-INHIBITING MEDICINAL COMPOSITION CONTAINING SAME | TEIJIN LIMITED (JP) | 1993-09-15 | — | — | EP | disclosed |
| US-4980287-A | ANTIINFLAMMATORY AGENTS; INHIBITOR OF DEGENERATION AND DESTRUCTION OF TISSUES | TEIJIN LIMITED (JP) | 1990-12-25 | — | — | US | disclosed |
| EP-0317645-A1 | 4H-3,1-BENZOXAZIN-4-ONE COMPOUNDS AND SERINE PROTEASE-INHIBITING MEDICINAL COMPOSITION CONTAINING SAME | TEIJIN LIMITED (JP) | 1989-05-31 | — | — | EP | disclosed |