Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | GSR | P00390 | 2/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17993400 | 0.89 | KDM4E (0.52) | KDM4EATML3MBTL1HTTMAPK1 | |
| SCHEMBL17993382 | 0.88 | KDM4E (0.50) | KDM4EATML3MBTL1HTTMAPK1 | |
| SCHEMBL17993396 | 0.83 | KDM4E (0.37) | KDM4EATML3MBTL1HTTMAPK1 | |
| SCHEMBL17993387 | 0.83 | KDM4E (0.53) | KDM4EATML3MBTL1HTTMAPK1 | |
| SCHEMBL13445180 | 0.81 | HTT (0.61) | KDM4EATML3MBTL1HTTMAPK1 | |
| SCHEMBL20040464 | 0.81 | MAPK1 (0.68) | KDM4EATML3MBTL1HTTMAPK1 | |
| SCHEMBL57391 | 0.79 | L3MBTL1 (0.73) | KDM4EATML3MBTL1HTTMAPK1 | |
| SCHEMBL29371952 | 0.79 | L3MBTL1 (0.73) | KDM4EATML3MBTL1HTTMAPK1 | |
| SCHEMBL29351958 | 0.79 | L3MBTL1 (0.73) | KDM4EATML3MBTL1HTTMAPK1 | |
| SCHEMBL15446479 | 0.79 | ESR1 (0.58) | KDM4EATML3MBTL1HTTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3053918-B1 | 2-carbazole substituted benzimidazoles for electronic applications | IDEMITSU KOSAN CO (JP) | 2018-04-11 | — | — | EP | disclosed |
| EP-3053918-A1 | 2-carbazole substituted benzimidazoles for electronic applications | Idemitsu Kosan Co., Ltd (JP) | 2016-08-10 | — | — | EP | disclosed |