Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 2/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | PRKACA | P17612 | 1/20 | 0.36 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17993400 | 0.90 | KDM4E (0.52) | KDM4EATML3MBTL1MAPK1HTT | |
| SCHEMBL17993389 | 0.88 | KDM4E (0.47) | KDM4EATML3MBTL1MAPK1HTT | |
| SCHEMBL30951244 | 0.86 | KDM4E (0.53) | KDM4EATML3MBTL1MAPK1HTT | |
| SCHEMBL17993396 | 0.84 | KDM4E (0.37) | KDM4EATML3MBTL1MAPK1HTT | |
| SCHEMBL13445180 | 0.83 | HTT (0.61) | KDM4EATML3MBTL1MAPK1HTT | |
| SCHEMBL29466048 | 0.83 | KDM4E (0.50) | KDM4EATML3MBTL1MAPK1HTT | |
| SCHEMBL28705086 | 0.83 | KDM4E (0.50) | KDM4EATML3MBTL1MAPK1HTT | |
| SCHEMBL17723973 | 0.83 | MAPK1 (0.69) | KDM4EATML3MBTL1MAPK1HTT | |
| SCHEMBL15371684 | 0.82 | ESR1 (0.58) | KDM4EATML3MBTL1MAPK1HTT | |
| SCHEMBL24531917 | 0.82 | L3MBTL1 (0.75) | KDM4EATML3MBTL1MAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3053918-A1 | 2-carbazole substituted benzimidazoles for electronic applications | Idemitsu Kosan Co., Ltd (JP) | 2016-08-10 | — | — | EP | disclosed |