Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HPGDS | O60760 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5990731 | 0.82 | ADORA1 (0.54) | ALDH1A1SMN1; SMN2LMNAMAPTMAPK1 | |
| SCHEMBL10205907 | 0.80 | KMT2A (0.53) | ALDH1A1SMN1; SMN2LMNAMAPTMAPK1 | |
| SCHEMBL14380306 | 0.80 | SMN1; SMN2 (0.48) | ALDH1A1SMN1; SMN2LMNAMAPTMAPK1 | |
| SCHEMBL17993487 | 0.80 | ALDH1A1 (0.58) | DPP4ALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL12854071 | 0.79 | SMN1; SMN2 (0.47) | ALDH1A1SMN1; SMN2LMNAMAPTMAPK1 | |
| SCHEMBL12854070 | 0.79 | SMN1; SMN2 (0.47) | ALDH1A1SMN1; SMN2LMNAMAPTMAPK1 | |
| SCHEMBL14380287 | 0.78 | SMN1; SMN2 (0.54) | ALDH1A1SMN1; SMN2LMNAMAPTMAPK1 | |
| SCHEMBL17993466 | 0.78 | ADORA1 (0.71) | DPP4ALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL21742766 | 0.77 | NPC1 (0.55) | DPP4ALDH1A1SMN1; SMN2HPGDSNPC1 | |
| SCHEMBL8946788 | 0.77 | MEN1 (0.55) | DPP4ALDH1A1SMN1; SMN2LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3054498-B1 | BISIMIDAZODIAZOCINES | IDEMITSU KOSAN CO (JP) | 2017-09-20 | — | — | EP | disclosed |
| WO-2016125110-A1 | BISIMIDAZOLODIAZOCINES | IDEMITSU KOSAN CO., LTD. (JP) | 2016-08-11 | — | — | WO | disclosed |
| EP-3054498-A1 | Bisimidazodiazocines | Idemitsu Kosan Co., Ltd. (JP) | 2016-08-10 | — | — | EP | disclosed |