SCHEMBL5990731

SCHEMBL5990731

c1ccc(-c2ncc(-c3ccccc3)c(-c3ccccc3)n2)cc1

nearest known ligand 0.61

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ADORA1 P30542 8/20 0.54
ADORA2A P29274 4/20 0.54
SMN1; SMN2 Q16637 3/20 0.50
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
NPC1 O15118 2/20 0.50
RAB9A P51151 2/20 0.50
NFKB1 P19838 1/20 0.50
NFKB2 Q00653 1/20 0.50
RELA Q04206 1/20 0.50
LMNA P02545 3/20 0.49
ALDH1A1 P00352 2/20 0.49
MAPT P10636 3/20 0.46
MAPK1 P28482 1/20 0.46
ATM Q13315 1/20 0.46
RECQL P46063 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17993487 0.89 ALDH1A1 (0.58) ADORA1ADORA2ASMN1; SMN2MEN1KMT2A
SCHEMBL27970612 0.89 NPC1 (0.59) ADORA1ADORA2ASMN1; SMN2MEN1KMT2A
SCHEMBL17445456 0.89 NPC1 (0.59) ADORA1ADORA2ASMN1; SMN2MEN1KMT2A
SCHEMBL29177828 0.88 ADORA1 (0.51) ADORA1ADORA2ASMN1; SMN2MEN1KMT2A
SCHEMBL14380287 0.87 SMN1; SMN2 (0.54) SMN1; SMN2MEN1KMT2ANPC1RAB9A
SCHEMBL10998119 0.85 KMT2A (0.61) ADORA1ADORA2AMEN1KMT2ALMNA
SCHEMBL27673770 0.84 NPC1 (0.45) ADORA1ADORA2ASMN1; SMN2MEN1KMT2A
SCHEMBL12854070 0.84 SMN1; SMN2 (0.47) ADORA1ADORA2ASMN1; SMN2MEN1KMT2A
SCHEMBL12854071 0.84 SMN1; SMN2 (0.47) SMN1; SMN2MEN1KMT2ANPC1RAB9A
SCHEMBL22058443 0.84 MAPT (0.49) ADORA1ADORA2ASMN1; SMN2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11393983-B2 Phenyl biphenylpyrimidine compound and an organic electroluminescent device using the same E-RAY OPTOELECTRONICS TECHNOLOGY CO., LTD. (TW) 2022-07-19 US claimed
CN-111454235-A Organic electroluminescent materials and devices 机光科技股份有限公司 2020-07-28 CN claimed
US-20200127211-A1 PHENYL BIPHENYLPYRIMIDINE COMPOUND AND AN ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME E-RAY OPTOELECTRONICS TECHNOLOGY CO., LTD. (TW) 2020-04-23 US claimed
CN-107325056-A A kind of method of the triphenyl pyrimidine derivatives of use ultrasonic wave synthesis in solid state 2,4,6 河南科技大学 2017-11-07 CN claimed
CN-103396404-B Compound using triphenylpyrimidine as core as well as preparation method and application thereof UNIV SOUTH CHINA TECH 2015-04-22 CN claimed
CN-103396404-A Compound using triphenylpyrimidine as core as well as preparation method and application thereof UNIV SOUTH CHINA TECH 2013-11-20 CN claimed
US-11575090-B2 Organic compound and organic electroluminescence device using the same LUMINESCENCE TECHNOLOGY CORP. (TW) 2023-02-07 US disclosed
CN-111454235-B Organic electroluminescent materials and devices 机光科技股份有限公司 2022-08-12 CN disclosed
US-11393983-B2 Phenyl biphenylpyrimidine compound and an organic electroluminescent device using the same E-RAY OPTOELECTRONICS TECHNOLOGY CO., LTD. (TW) 2022-07-19 US disclosed
US-11393983-B2 Phenyl biphenylpyrimidine compound and an organic electroluminescent device using the same E-RAY OPTOELECTRONICS TECHNOLOGY CO., LTD. (TW) 2022-07-19 US disclosed
CN-109928960-B Non-aromatic amine high exciton utilization rate small molecule material and application 华南理工大学 2022-05-24 CN disclosed
US-11322695-B2 Ink composition for organic light-emitting device, organic light-emitting device including film formed by using the ink composition, and method of manufacturing the organic light-emitting device SAMSUNG ELECTRONICS CO., LTD. (KR) 2022-05-03 US disclosed
US-20220131089-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME LUMINESCENCE TECHNOLOGY CORPORATION (TW) 2022-04-28 US disclosed
EP-1549112-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2005-06-29 EP disclosed
US-6706215-B1 2-(2'-HYDROXYPHENYL)-1,3-PYRIMIDINE DERIVATIVE CIBA SPECIALTY CHEMICALS CORPORATION 2004-03-16 US disclosed
US-6194493-B1 STABILILZATION OF ORGANIC MATERIALS, PHOTOSTABILITY CLARIANT GMBH (DE) 2001-02-27 US disclosed
US-6172232-B1 Light stabilizers based on sterically hindered amines CLARIANT GMBH (DE) 2001-01-09 US disclosed
EP-0900794-A1 Light stabilizers based on sterically hindered amines Clariant GmbH (DE) 1999-03-10 EP disclosed
EP-0900824-A1 4-Hydroxyquinoline-3-carboxylic acid derivatives as light stabilizers Clariant GmbH (DE) 1999-03-10 EP disclosed
US-5753729-A COATING COMPOSITION COMPRISING ORGANIC POLYMER BINDER, 2-(2*-HYDROXYPHENYL)PYRIMIDINE STABILIZER CIBA SPECIALTY CHEMICALS CORPORATION 1998-05-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11393983-B2 Phenyl biphenylpyrimidine compound and an organic electroluminescent device using the same DPYD, NUDT1, PNP ADORA1 434/4885ADORA2A 1073/4885SMN1; SMN2 2555/4885
US-20220131089-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME OR10J3, PIEZO1, ODC1 ADORA1 3211/4885ADORA2A 4641/4885SMN1; SMN2 3228/4885
US-20200127211-A1 PHENYL BIPHENYLPYRIMIDINE COMPOUND AND AN ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME DPYD, NUDT1, PNP ADORA1 434/4885ADORA2A 1073/4885SMN1; SMN2 2555/4885
US-11575090-B2 Organic compound and organic electroluminescence device using the same OR10J3, PIEZO1, ODC1 ADORA1 3211/4885ADORA2A 4641/4885SMN1; SMN2 3228/4885
US-11322695-B2 Ink composition for organic light-emitting device, organic light-emitting device including film formed by using the ink composition, and method of manufacturing the organic light-emitting device TYR, IK, TH ADORA1 3760/4885ADORA2A 4692/4885SMN1; SMN2 3319/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.