Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.45 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | DRD3 | P35462 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MET | P08581 | 4/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | CSF1R | P07333 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17233735 | 0.83 | RAB9A (0.50) | RAB9AHDAC1DRD2DRD3PKM | |
| SCHEMBL14817504 | 0.82 | RAB9A (0.47) | RAB9AHDAC1DRD2DRD3PKM | |
| SCHEMBL362809 | 0.81 | RAB9A (0.55) | RAB9AHDAC1DRD2DRD3PKM | |
| SCHEMBL306677 | 0.80 | RAB9A (0.54) | RAB9AHDAC1DRD2DRD3PKM | |
| SCHEMBL13926363 | 0.80 | RAB9A (0.50) | RAB9AHDAC1DRD2DRD3PKM | |
| SCHEMBL14817514 | 0.78 | RAB9A (0.46) | RAB9AHDAC1DRD2DRD3PKM | |
| SCHEMBL10172974 | 0.75 | MET (0.44) | RAB9AHDAC1DRD2DRD3PKM | |
| SCHEMBL14873198 | 0.75 | RAB9A (0.47) | RAB9AHDAC1DRD2DRD3PKM | |
| SCHEMBL17993541 | 0.75 | RAB9A (0.49) | RAB9AHDAC1DRD2DRD3PKM | |
| SCHEMBL5097841 | 0.75 | RAB9A (0.53) | RAB9AHDAC1DRD2DRD3PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2426108-B1 | Processes and intermediates for preparing fused heterocyclic kinase inhibitors | METHYLGENE INC (CA) | 2016-08-10 | — | — | EP | disclosed |