Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 16/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 13/20 | 0.51 |
| ▸ | SLC22A12 | Q96S37 | 4/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17258767 | 0.83 | PTGS1 (0.55) | PTGS1PTGS2SLC22A12 | |
| SCHEMBL23027515 | 0.76 | AOC1 (0.44) | — | |
| SCHEMBL12320185 | 0.75 | PTGS1 (0.68) | PTGS1PTGS2 | |
| SCHEMBL521538 | 0.73 | PTGS1 (0.60) | PTGS1PTGS2SLC22A12 | |
| SCHEMBL21048790 | 0.72 | SLC22A12 (0.63) | PTGS1PTGS2SLC22A12 | |
| SCHEMBL14479712 | 0.72 | MEN1 (0.40) | — | |
| SCHEMBL12836473 | 0.72 | SLC6A2 (0.54) | — | |
| SCHEMBL16547439 | 0.72 | SLC6A2 (0.54) | — | |
| SCHEMBL14960632 | 0.70 | PTGS1 (0.67) | PTGS1PTGS2 | |
| SCHEMBL14627251 | 0.70 | PTGS1 (0.53) | PTGS1PTGS2SLC22A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2146779-B1 | SULFONYL AMIDE DERIVATIVES FOR THE TREATMENT OF ABNORMAL CELL GROWTH | PFIZER PROD INC (US) | 2016-08-10 | — | — | EP | disclosed |