Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 20/20 | 0.68 |
| ▸ | PTGS2 | P35354 | 15/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12320158 | 0.79 | PTGS1 (0.53) | PTGS1PTGS2 | |
| SCHEMBL14960632 | 0.78 | PTGS1 (0.67) | PTGS1PTGS2 | |
| SCHEMBL17258767 | 0.77 | PTGS1 (0.55) | PTGS1PTGS2 | |
| SCHEMBL23889288 | 0.77 | AOC1 (0.69) | PTGS1PTGS2 | |
| SCHEMBL5806458 | 0.76 | PTGS1 (0.55) | PTGS1PTGS2 | |
| SCHEMBL19788231 | 0.76 | PTGS1 (0.55) | PTGS1PTGS2 | |
| SCHEMBL10310091 | 0.76 | KDM4C (0.61) | PTGS1PTGS2 | |
| SCHEMBL15087874 | 0.76 | AOC1 (0.71) | PTGS1PTGS2 | |
| SCHEMBL17993893 | 0.75 | PTGS1 (0.52) | PTGS1PTGS2 | |
| SCHEMBL6120121 | 0.74 | PTGS1 (0.69) | PTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9169246-B2 | Pyrazoloquinolinone derivatives, preparation thereof and therapeutic use thereof | SANOFI (FR) | 2015-10-27 | — | — | US | disclosed |
| US-20130079337-A1 | PYRAZOLOQUINOLINONE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2013-03-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130079337-A1 | PYRAZOLOQUINOLINONE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | CYP11B2, COQ8A, CYP1A2 | PTGS1 287/4885PTGS2 540/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.