SCHEMBL17995261

SCHEMBL17995261

CN1CCC(=O)CC1C(=O)O

nearest known ligand 0.40

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
DRD5 P21918 1/20 0.40
ACE P12821 3/20 0.33
ITGB1 P05556 1/20 0.32
ITGA5 P08648 1/20 0.32
TSHR P16473 1/20 0.32
MAPT P10636 1/20 0.32
POLB P06746 2/20 0.31
MMP2 P08253 1/20 0.31
ANPEP P15144 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13703425 0.79 MMP2 (0.49) POLBMMP2ANPEP
SCHEMBL24635839 0.79 MMP2 (0.49) POLBMMP2ANPEP
SCHEMBL10137597 0.79 MMP2 (0.40) DRD5ACEITGB1ITGA5TSHR
SCHEMBL13688455 0.79 MMP2 (0.40) DRD5ACEITGB1ITGA5TSHR
SCHEMBL27607180 0.78
SCHEMBL5223810 0.76
SCHEMBL15542290 0.76
SCHEMBL5224593 0.76
SCHEMBL18084383 0.74
SCHEMBL30346218 0.73 TSHR (0.39) ITGB1ITGA5TSHRMMP2ANPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230133817-A1 MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS RQX PHARMACEUTICALS INC (US) 2023-05-04 US disclosed
US-20170097567-A1 METHOD FOR PRODUCING POLYMER SHIN-ETSU CHEMICAL CO., LTD. (JP) 2017-04-06 US disclosed
US-20160229940-A1 POLYMER, RESIST COMPOSITION, AND PATTERN FORMING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2016-08-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230133817-A1 MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS MRPL21, PEPD, CTSC DRD5 4613/4885ACE 170/4885ITGB1 2871/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.