⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5223810 | 1.00 | — | — | |
| SCHEMBL15542290 | 1.00 | — | — | |
| SCHEMBL20723785 | 0.82 | ALDH1A1 (0.35) | — | |
| SCHEMBL20723786 | 0.82 | ALDH1A1 (0.35) | — | |
| SCHEMBL4418517 | 0.80 | MMP2 (0.46) | — | |
| SCHEMBL30346218 | 0.80 | TSHR (0.39) | — | |
| SCHEMBL22518861 | 0.80 | — | — | |
| SCHEMBL22518860 | 0.80 | — | — | |
| SCHEMBL1250785 | 0.79 | MMP2 (0.36) | — | |
| SCHEMBL6921106 | 0.79 | MMP2 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2026098560-A2 | BENZENE-CONTAINING POLYCYCLIC DERIVATIVE MODULATOR, PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翰森生物医药科技有限公司 | 2026-05-15 | — | — | WO | disclosed |
| EP-4065113-B1 | (R)-4-(1-(6-(4-(TRIFLUOROMETHYL)BENZYL)-6-AZASPIRO[2.5]OCTANE-5-CARBOXAMIDO)-CYCLOPROPYL) BENZOIC ACID OR ITS SALT ALSO IN POLYMORPHIC FORM A FOR USE IN THE PREVENTION OF HETEROTOPIC OSSIFICATION | Rottapharm Biotech Srl (IT) | 2024-01-10 | — | — | EP | disclosed |
| US-20230357271-A1 | MACROCYCLIC COMPOUND | ASAHI KASEI PHARMA CORPORATION (JP) | 2023-11-09 | — | — | US | disclosed |
| EP-4223368-A1 | MACROCYCLE COMPOUND | Asahi Kasei Pharma Corporation (JP) | 2023-08-09 | — | — | EP | disclosed |
| US-20230234958-A1 | SHP2 PHOSPHATASE INHIBITORS AND METHODS OF USE THEREOF | D. E. SHAW RESEARCH, LLC | 2023-07-27 | — | — | US | disclosed |
| WO-2023137225-A1 | BTK DEGRADER | NEWAVE PHARMACEUTICAL INC. (US) | 2023-07-20 | — | — | WO | disclosed |
| US-11685746-B2 | Heteroaryl compounds for treating Huntington's disease | PTC THERAPEUTICS, INC. (US) | 2023-06-27 | — | — | US | disclosed |
| US-11590114-B2 | Pharmaceutical combination of an EP4 antagonist and immune checkpoint inhibitors for the treatment of tumours | ROTTAPHARM BIOTECH S.R.L. (IT) | 2023-02-28 | — | — | US | disclosed |
| US-20230028519-A1 | (R)-4-(1-(6-(4-(TRIFLUOROMETHYL)BENZYL)-6-AZASPIRO[2.5] OCTANE-5-CARBOXAMIDO)-CYCLOPROPYL) BENZOIC ACID OR ITS SALT ALSO IN POLYMORPHIC FORM A FOR USE IN THE PREVENTION OF HETEROTOPIC OSSIFICATION | ROTTAPHARM BIOTECH S.R.L. (IT) | 2023-01-26 | — | — | US | disclosed |
| US-20220340576-A1 | SHP2 PHOSPHATASE INHIBITORS AND METHODS OF USE THEREOF | RELAY THERAPEUTICS, INC. | 2022-10-27 | — | — | US | disclosed |
| CN-104940202-B | Inhibitors of influenza viruses replication | 沃泰克斯药物股份有限公司 | 2018-10-16 | — | — | CN | disclosed |
| WO-2018115275-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF KINETOPLASTID INFECTION | IRBM SCIENCE PARK S.P.A. (IT) | 2018-06-28 | — | — | WO | disclosed |
| US-20180162855-A1 | PDD AND BPD COMPOUNDS | PHEON THERAPEUTICS LTD (GB) | 2018-06-14 | — | — | US | disclosed |
| CN-104151312-B | Inhibitors of influenza viruses replication | 沃泰克斯药物股份有限公司 | 2016-06-15 | — | — | CN | disclosed |
| CN-104940202-A | Inhibitors of influenza viruses replication | VERTEX PHARMA | 2015-09-30 | — | — | CN | disclosed |
| CN-104922128-A | INHIBITORS OF INFLUENZA VIRUSES REPLICATION | VERTEX PHARMA | 2015-09-23 | — | — | CN | disclosed |
| CN-102458408-B | Inhibitors of influenza virus replication | VERTEX PHARMA | 2015-06-03 | — | — | CN | disclosed |
| CN-102458408-A | Inhibitors of influenza virus replication | VERTEX PHARMA | 2012-05-16 | — | — | CN | disclosed |
| EP-1814893-A2 | NOVEL LINCOMYCIN DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY | Vicuron Pharmaceuticals, Inc. (US) | 2007-08-08 | — | — | EP | disclosed |
| WO-2006055070-A2 | NOVEL LINCOMYCIN DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY | VICURON PHARMACEUTICALS INC. (US) | 2006-05-26 | — | — | WO | disclosed |