SCHEMBL17995347

SCHEMBL17995347

c1ccc(-c2ccc(-c3nc(-c4ccccc4)nc(-c4nc(-c5ccccc5)nc(-c5cc6ccccc6c6ccccc56)n4)n3)cc2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 1/20 0.49
ALDH1A1 P00352 6/20 0.44
MEN1 O00255 5/20 0.44
KMT2A Q03164 5/20 0.44
MAPT P10636 5/20 0.44
HPGD P15428 5/20 0.44
ATM Q13315 2/20 0.42
L3MBTL1 Q9Y468 3/20 0.42
GPR84 Q9NQS5 1/20 0.42
LMNA P02545 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
NPC1 O15118 1/20 0.41
RECQL P46063 1/20 0.41
RAB9A P51151 1/20 0.41
KDM4E B2RXH2 3/20 0.41
NTSR1 P30989 1/20 0.41
MPI P34949 1/20 0.41
TSHR P16473 3/20 0.40
ADORA2A P29274 3/20 0.40
ADORA1 P30542 3/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21394564 0.98 CYP11B1 (0.50) CYP11B1ALDH1A1MEN1KMT2AMAPT
SCHEMBL21394109 0.98 CYP11B1 (0.50) CYP11B1ALDH1A1MEN1KMT2AMAPT
SCHEMBL17932612 0.98 CYP11B1 (0.50) CYP11B1ALDH1A1MEN1KMT2AMAPT
SCHEMBL18327507 0.98 CYP11B1 (0.50) CYP11B1ALDH1A1MEN1KMT2AMAPT
SCHEMBL17995339 0.96 CYP11B1 (0.51) CYP11B1ALDH1A1MEN1KMT2AMAPT
SCHEMBL17932656 0.95 CYP11B1 (0.47) CYP11B1ALDH1A1MEN1KMT2AMAPT
SCHEMBL17932621 0.95 CYP11B1 (0.47) CYP11B1ALDH1A1MEN1KMT2AMAPT
SCHEMBL18327468 0.94 CYP11B1 (0.53) CYP11B1ALDH1A1MEN1KMT2AMAPT
SCHEMBL19271420 0.94 CYP11B1 (0.53) CYP11B1ALDH1A1MEN1KMT2AMAPT
SCHEMBL24306963 0.93 CYP11B1 (0.46) CYP11B1ALDH1A1MEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10418562-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2019-09-17 US disclosed
US-20160233429-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2016-08-11 US disclosed
US-20160233429-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2016-08-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10418562-B2 Organic electroluminescent materials and devices NBAS, TBCB, SLC1A2 CYP11B1 2289/4885ALDH1A1 1352/4885MEN1 1915/4885
US-20160233429-A1 Organic Electroluminescent Materials and Devices NBAS, TBCB, SLC1A2 CYP11B1 2289/4885ALDH1A1 1352/4885MEN1 1915/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.