Oxirane

Oxirane

SCHEMBL17997374

C/C=C(\C)C(=O)O.C/C=C(\C)C(=O)O.C1CO1

nearest known ligand 0.37

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.37
PTGS1 P23219 1/20 0.34
AKR1C3 P42330 1/20 0.34
MAPT P10636 1/20 0.32
FFAR3 O14843 1/20 0.32
LCK P06239 1/20 0.32
FYN P06241 1/20 0.32
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Oxirane SCHEMBL1811077 1.00 SMN1; SMN2 (0.37) SMN1; SMN2PTGS1AKR1C3MAPTFFAR3
Oxirane SCHEMBL17997377 1.00 SMN1; SMN2 (0.37) SMN1; SMN2PTGS1AKR1C3MAPTFFAR3
Fluoride SCHEMBL27700715 0.88
Tetrahydrofuran SCHEMBL20843627 0.87 ALDH1A1 (0.38) SMN1; SMN2PTGS1AKR1C3
SCHEMBL28550396 0.85 ALDH1A1 (0.36) SMN1; SMN2PTGS1AKR1C3
Bicarbonate SCHEMBL3266218 0.85 PTGS1 (0.39) PTGS1AKR1C3MAPTFFAR3LCK
SCHEMBL18814 0.85
SCHEMBL133954 0.85
SCHEMBL871351 0.85 FFAR3 (0.43) PTGS1AKR1C3MAPTFFAR3LCK
SCHEMBL338643 0.85 FFAR3 (0.43) PTGS1AKR1C3MAPTFFAR3LCK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2805366-B1 SEPARATOR COMPRISING A POROUS LAYER AND A PROCEDURE FOR ITS PREPARATION SIHL GMBH (DE) 2016-08-24 EP claimed