Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 11/20 | 0.58 |
| ▸ | BCL9 | O00512 | 4/20 | 0.46 |
| ▸ | CTNNB1 | P35222 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.43 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12471111 | 0.88 | HRH3 (0.56) | HRH3BCL9CTNNB1NPC1RAB9A | |
| SCHEMBL12471106 | 0.88 | HRH3 (0.56) | HRH3BCL9CTNNB1NPC1RAB9A | |
| SCHEMBL29700588 | 0.87 | HRH3 (0.67) | HRH3KMT2AMEN1L3MBTL3L3MBTL1 | |
| SCHEMBL12471398 | 0.84 | HRH3 (0.57) | HRH3NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL12471396 | 0.84 | HRH3 (0.57) | HRH3NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL17739185 | 0.81 | KDM4E (0.51) | HRH3 | |
| SCHEMBL18532923 | 0.81 | KDM4E (0.51) | HRH3 | |
| SCHEMBL17997536 | 0.80 | ENPP2 (0.50) | KMT2AMEN1 | |
| SCHEMBL16667317 | 0.80 | ENPP2 (0.50) | KMT2AMEN1 | |
| SCHEMBL11942498 | 0.79 | HRH3 (0.50) | HRH3KMT2AMEN1TRPV6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3150590-B1 | S1P MODULATING AGENTS | BIOGEN MA INC (US) | 2019-10-16 | — | — | EP | claimed |
| EP-2672823-B1 | S1P MODULATING AGENTS | BIOGEN MA INC (US) | 2016-08-24 | — | — | EP | claimed |