Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 18/20 | 0.58 |
| ▸ | SUCNR1 | Q9BXA5 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17998288 | 0.85 | CTSA (0.67) | CTSA | |
| SCHEMBL2875456 | 0.83 | MMEL1 (0.64) | CTSA | |
| SCHEMBL2875462 | 0.83 | MMEL1 (0.64) | CTSA | |
| SCHEMBL17998478 | 0.81 | CTSA (0.66) | CTSA | |
| SCHEMBL17998476 | 0.81 | CTSA (0.66) | CTSA | |
| SCHEMBL27761114 | 0.79 | CTSA (0.62) | CTSASUCNR1 | |
| SCHEMBL3994930 | 0.77 | CTSA (0.57) | CTSASUCNR1 | |
| SCHEMBL14952843 | 0.76 | MMEL1 (0.51) | — | |
| SCHEMBL5926505 | 0.75 | CTSA (0.60) | CTSASUCNR1 | |
| SCHEMBL15637633 | 0.74 | CTSA (1.00) | CTSASUCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2667870-B1 | SUBSTITUTED 3-HETEROAROYLAMINO-PROPIONIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI SA (FR) | 2016-08-24 | — | — | EP | disclosed |