SCHEMBL18007115

SCHEMBL18007115

C=C(CCC(=O)O)C(=O)OCCC

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR3 O14843 1/20 0.41
HDAC3 O15379 1/20 0.41
HDAC1 Q13547 1/20 0.41
HDAC2 Q92769 1/20 0.41
HDAC8 Q9BY41 1/20 0.41
TSHR P16473 6/20 0.40
HCAR2 Q8TDS4 1/20 0.38
THRB P10828 1/20 0.37
AKR1B1 P15121 1/20 0.37
GAA P10253 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
LMNA P02545 2/20 0.36
ALKBH5 Q6P6C2 1/20 0.36
SUCNR1 Q9BXA5 1/20 0.36
EGLN1 Q9GZT9 1/20 0.36
GPR84 Q9NQS5 6/20 0.35
PPARG P37231 6/20 0.35
PPARD Q03181 6/20 0.35
PPARA Q07869 6/20 0.35
HDAC11 Q96DB2 5/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18007141 0.89 AKR1B1 (0.43) TSHRAKR1B1GPR84PPARGPPARD
SCHEMBL18007133 0.89 TSHR (0.50) TSHRHCAR2AKR1B1GPR84PPARG
SCHEMBL3476011 0.85 TSHR (0.44) FFAR3HDAC3HDAC1HDAC2HDAC8
Succinic Acid SCHEMBL6175052 0.84 TSHR (0.58) FFAR3HDAC3HDAC1HDAC2HDAC8
SCHEMBL17533547 0.84 MAPT (0.45) TSHRHCAR2THRBLMNAALDH1A1
SCHEMBL11701319 0.84 FFAR3 (0.46) FFAR3HDAC3HDAC1HDAC2HDAC8
SCHEMBL6023253 0.83 ALDH1A1 (0.45) FFAR3HDAC3HDAC1HDAC2HDAC8
SCHEMBL5716610 0.82 TSHR (0.41) TSHRHCAR2THRBGAASMN1; SMN2
SCHEMBL3477341 0.82 TSHR (0.50) TSHRHCAR2THRBALDH1A1
SCHEMBL481223 0.82 TSHR (0.41) FFAR3HDAC3HDAC1HDAC2HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107257813-B Block copolymers having surface active anchoring groups, compositions and methods thereof AZ电子材料卢森堡有限公司 2020-08-21 CN disclosed
EP-3259292-B1 BLOCK COPOLYMERS WITH SURFACE-ACTIVE JUNCTION GROUPS, COMPOSITIONS AND PROCESSES THEREOF AZ ELECTRONIC MAT LUXEMBOURG SARL (LU) 2020-04-08 EP disclosed
US-10259907-B2 Block copolymers with surface-active junction groups, compositions and processes thereof AZ ELECTRONIC MATERIALS (LUXEMBOURG) S.À R.L. (LU) 2019-04-16 US disclosed
EP-3259292-A1 BLOCK COPOLYMERS WITH SURFACE-ACTIVE JUNCTION GROUPS, COMPOSITIONS AND PROCESSES THEREOF AZ Electronic Materials Luxembourg S.à.r.l. (LU) 2017-12-27 EP disclosed
WO-2017144385-A1 BLOCK COPOLYMERS WITH LINEAR SURFACE-ACTIVE JUNCTION GROUPS, COMPOSITIONS AND PROCESSES THEREOF AZ Electronic Materials (Luxembourg) S.à.r.l. (LU) 2017-08-31 WO disclosed
WO-2016131900-A1 BLOCK COPOLYMERS WITH SURFACE-ACTIVE JUNCTION GROUPS, COMPOSITIONS AND PROCESSES THEREOF AZ Electronic Materials (Luxembourg) S.à.r.l. (LU) 2016-08-25 WO disclosed
US-20160244557-A1 BLOCK COPOLYMERS WITH SURFACE-ACTIVE JUNCTION GROUPS, COMPOSITIONS AND PROCESSES THEREOF AZ ELECTRONIC MATERIALS (LUXEMBOURG) S. a. r. l. (LU) 2016-08-25 US disclosed