SCHEMBL1800780

SCHEMBL1800780

OCC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.38

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.38
THRB P10828 1/20 0.38
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
MMP1 P03956 1/20 0.32
MMP2 P08253 1/20 0.32
MMP9 P14780 1/20 0.32
MMP8 P22894 1/20 0.32
MMP13 P45452 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7073599 1.00 LMNA (0.38) LMNATHRBCA1CA2MMP1
SCHEMBL1986351 1.00 LMNA (0.38) LMNATHRBCA1CA2MMP1
SCHEMBL1983621 1.00 LMNA (0.38) LMNATHRBCA1CA2MMP1
SCHEMBL500248 1.00 LMNA (0.38) LMNATHRBCA1CA2MMP1
SCHEMBL6236854 1.00 LMNA (0.38) LMNATHRBCA1CA2MMP1
SCHEMBL847419 1.00 LMNA (0.38) LMNATHRBCA1CA2MMP1
SCHEMBL395116 1.00 LMNA (0.38) LMNATHRBCA1CA2MMP1
SCHEMBL6233841 1.00 LMNA (0.38) LMNATHRBCA1CA2MMP1
SCHEMBL916204 1.00 LMNA (0.38) LMNATHRBCA1CA2MMP1
SCHEMBL395716 1.00 LMNA (0.38) LMNATHRBCA1CA2MMP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200041393-A1 METHOD OF CONCENTRATING ANALYTES, AND SYSTEM FOR CONCENTRATING AND DETECTING ANALYTES COMMISSARIAT À L'ÉNERGIE ATOMIQUE ET AUX ÉNERGIES ALTERNATIVES (CEA) (FR) 2020-02-06 US claimed
US-20030194378-A1 Novel aerosol formulation containing a polar fluorinated molecule ASTRAZENECA AB (SE) 2003-10-16 US claimed
EP-1303258-A1 NOVEL AEROSOL FORMULATION CONTAINING A POLAR FLUORINATED MOLECULE AstraZeneca AB (SE) 2003-04-23 EP claimed
WO-2002003958-A1 NOVEL AEROSOL FORMULATION CONTAINING A POLAR FLUORINATED MOLECULE ASTRAZENECA AB (SE) 2002-01-17 WO claimed
US-11402307-B2 Method for concentrating analytes COMMISSARIAT À L'ÉNERGIE ATOMIQUE ET AUX ÉNERGIES ALTERNATIVES (CEA) (FR) 2022-08-02 US disclosed
US-20200041393-A1 METHOD OF CONCENTRATING ANALYTES, AND SYSTEM FOR CONCENTRATING AND DETECTING ANALYTES COMMISSARIAT À L'ÉNERGIE ATOMIQUE ET AUX ÉNERGIES ALTERNATIVES (CEA) (FR) 2020-02-06 US disclosed
US-10384937-B2 Method of generating hydrogen from the reaction of stabilized aluminum nanoparticles with water and method of forming stabilized aluminum nanoparticles UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 2019-08-20 US disclosed
US-9492989-B2 Composition and method for manufacture of a fibrous polyurethane composite product HAUPT ROBERT A (US) 2016-11-15 US disclosed
EP-2099408-B1 FLUOROPOLYMER-BASED EMULSIONS FOR THE INTRAVENOUS DELIVERY OF FLUORINATED VOLATILE ANESTHETICS WISCONSIN ALUMNI RES FOUND (US) 2016-10-05 EP disclosed
US-20150266730-A1 METHOD OF GENERATING HYDROGEN FROM THE REACTION OF STABILIZED ALUMINUM NANOPARTICLES WITH WATER AND METHOD OF FORMING STABILIZED ALUMINUM NANOPARTICLES UNIVERSITY OF DAYTON 2015-09-24 US disclosed
US-9011572-B1 Method of generating hydrogen from the reaction of stabilized aluminum nanoparticles with water and method of forming stabilized aluminum nanoparticles UNIVERSITY OF DAYTON (US) 2015-04-21 US disclosed
US-9000048-B2 Fluoropolymer-based emulsions for the intravenous delivery of fluorinated volatile anesthetics WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2015-04-07 US disclosed
EP-1036790-A1 Perfluoro group-containing compounds and hardened polymer of the same Kyoeisha Chemical Co., Ltd. (JP) 2000-09-20 EP disclosed
US-6084057-A POLYAMIC ACID WHERE THE AMINE COMPONENT IS A POLARIZABLE DIAMINE HAVING A FLUOROCARBON MOIETY AND POLAR GROUP COMPRISING A PI ELECTRON SYSTEM CONTAINING AT LEAST ONE HETEROATOM; POLYIMIDE THEREFROM ELSICON, INC. (US) 2000-07-04 US disclosed
US-6043337-A FIR LIQUID CRYSTAL DISPLAY ELEMENTS ELSICON, INC. (US) 2000-03-28 US disclosed
US-5929201-A A POLYAMIC ACID IS THE REACTION PRODUCT OF A FLUORINATED MONOAMINE, A DIAMINE AND ATLEAST ONE TETERACARBOXYLIC DIANHYDRIDE ELSICON, INC. (US) 1999-07-27 US disclosed
WO-1998053361-A2 POLARIZABLE AMINES AND POLYIMIDES FOR OPTICAL ALIGNMENT OF LIQUID CRYSTALS ALLIANT TECHSYSTEMS INC. (US) 1998-11-26 WO disclosed
WO-1998052990-A1 FLUORINATED AMINE PRODUCTS ALLIANT TECHSYSTEMS INC. (US) 1998-11-26 WO disclosed
EP-0837085-A1 POLYCARBONATE-BASE POLYMER, PRODUCTION PROCESS, RESIN COATING FLUID PREPARED THEREFROM, AND ELECTROPHOTOGRAPHIC PHOTORECEPTOR PREPARED THEREFROM IDEMITSU KOSAN COMPANY LIMITED (JP) 1998-04-22 EP disclosed
US-5512207-A Azaaromatic compounds, process for their preparation, and their use in liquid-crystalline mixtures HOECHST AKTIENGESELLSCHAFT (DE) 1996-04-30 US disclosed