SCHEMBL6236854

SCHEMBL6236854

OCC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.38

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.38
THRB P10828 1/20 0.38
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
MMP1 P03956 1/20 0.32
MMP2 P08253 1/20 0.32
MMP9 P14780 1/20 0.32
MMP8 P22894 1/20 0.32
MMP13 P45452 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7073599 1.00 LMNA (0.38) LMNATHRBCA1CA2MMP1
SCHEMBL1986351 1.00 LMNA (0.38) LMNATHRBCA1CA2MMP1
SCHEMBL1983621 1.00 LMNA (0.38) LMNATHRBCA1CA2MMP1
SCHEMBL500248 1.00 LMNA (0.38) LMNATHRBCA1CA2MMP1
SCHEMBL847419 1.00 LMNA (0.38) LMNATHRBCA1CA2MMP1
SCHEMBL395116 1.00 LMNA (0.38) LMNATHRBCA1CA2MMP1
SCHEMBL6233841 1.00 LMNA (0.38) LMNATHRBCA1CA2MMP1
SCHEMBL916204 1.00 LMNA (0.38) LMNATHRBCA1CA2MMP1
SCHEMBL395716 1.00 LMNA (0.38) LMNATHRBCA1CA2MMP1
SCHEMBL1800780 1.00 LMNA (0.38) LMNATHRBCA1CA2MMP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1036790-B1 Perfluoro group-containing compounds and hardened polymer of the same KYOEISHA CHEMICAL CO LTD (JP) 2005-06-01 EP disclosed
EP-1036790-A1 Perfluoro group-containing compounds and hardened polymer of the same Kyoeisha Chemical Co., Ltd. (JP) 2000-09-20 EP disclosed