Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.56 |
| ▸ | CDK9 | P50750 | 1/20 | 0.56 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 6/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | ATM | Q13315 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11657220 | 0.92 | MAPT (0.68) | POLBSMN1; SMN2TSHRMEN1KMT2A | |
| SCHEMBL9068980 | 0.86 | POLB (0.61) | POLBSMN1; SMN2TP53EPHX1TSHR | |
| SCHEMBL9157991 | 0.83 | POLB (0.57) | POLBSMN1; SMN2TP53EPHX1TSHR | |
| SCHEMBL9676988 | 0.83 | POLB (0.57) | POLBSMN1; SMN2TP53EPHX1TSHR | |
| SCHEMBL11174713 | 0.83 | MEN1 (0.61) | POLBSMN1; SMN2TP53EPHX1TSHR | |
| SCHEMBL628621 | 0.83 | ALDH1A1 (0.61) | POLBSMN1; SMN2TP53EPHX1TSHR | |
| SCHEMBL9158000 | 0.83 | POLB (0.57) | POLBSMN1; SMN2TP53EPHX1TSHR | |
| SCHEMBL6864880 | 0.80 | ALDH1A1 (0.63) | POLBSMN1; SMN2TP53EPHX1TSHR | |
| SCHEMBL11380030 | 0.80 | POLB (0.59) | POLBSMN1; SMN2TP53EPHX1TSHR | |
| SCHEMBL9614167 | 0.79 | POLB (0.53) | POLBSMN1; SMN2TP53EPHX1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7951602-B2 | Mass defect labeling and methods of use thereof | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2011-05-31 | — | — | US | disclosed |
| US-20090061523-A1 | MASS DEFECT LABELING AND METHODS OF USE THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2009-03-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090061523-A1 | MASS DEFECT LABELING AND METHODS OF USE THEREOF | PTMS, SPPL2B, NPPA | POLB 1005/4885SMN1; SMN2 368/4885TP53 37/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.