SCHEMBL1800944

SCHEMBL1800944

O=C(O)C1CC(Br)=NN1c1ncccc1Cl

nearest known ligand 0.43

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ SMN1; SMN2 Q16637 1/20 0.43
▸ MALT1 Q9UDY8 4/20 0.42
▸ TRPA1 O75762 2/20 0.37
▸ TRPV1 Q8NER1 1/20 0.35
▸ PHGDH O43175 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29402480 1.00 SMN1; SMN2 (0.43) SMN1; SMN2MALT1TRPA1TRPV1PHGDH
SCHEMBL10300033 0.90 MALT1 (0.39) SMN1; SMN2MALT1TRPA1TRPV1PHGDH
SCHEMBL30301254 0.86 MALT1 (0.43) SMN1; SMN2MALT1TRPA1TRPV1
SCHEMBL6909143 0.86 MALT1 (0.43) SMN1; SMN2MALT1TRPA1TRPV1
SCHEMBL28966441 0.85 MALT1 (0.43) SMN1; SMN2MALT1TRPA1TRPV1
SCHEMBL31690628 0.85 MALT1 (0.43) SMN1; SMN2MALT1TRPA1TRPV1
SCHEMBL28401566 0.85 MALT1 (0.40) MALT1TRPV1PHGDH
SCHEMBL10300026 0.84 MALT1 (0.43) SMN1; SMN2MALT1TRPA1TRPV1PHGDH
SCHEMBL10300248 0.84 MALT1 (0.36) MALT1TRPA1TRPV1PHGDH
SCHEMBL1581329 0.82 CYP2C19 (0.44) MALT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4017847-B1 PROCESS FOR THE PREPARATION OF CARBOXYLIC ACID DERIVATIVES OF 3-BROMO-4,5-DIHYDRO-1H-PYRAZOLES FMC CORP (US) 2025-10-01 — — EP claimed
US-20240067624-A1 PROCESS FOR PREPARATION OF INSECTICIDAL ANTHRANILAMIDES UPL LTD (IN) 2024-02-29 — — US claimed
CN-116724015-A Process for preparing insecticidal anthranilamides UPL有限公司 2023-09-08 — — CN claimed
CN-115057844-A Preparation method of chlorantraniliprole 江苏七洲绿色科技研究院有限公司 2022-09-16 — — CN claimed
CN-114217000-A High performance liquid chromatography detection method for chlorantraniliprole in solution 重庆华歌生物化学有限公司 2022-03-22 — — CN claimed
CN-113447602-A Cyantraniliprole and metabolite residue detection method thereof 广东省农业科学院植物保护研究所 2021-09-28 — — CN claimed
CN-111440144-A Method for industrially producing bromopyrazolic acid through micro-channel 山东华科化工有限公司 2020-07-24 — — CN claimed
EP-4472964-A1 METHODS FOR THE PREPARATION OF ETHYL 3-BROMO-1-(3-CHLOROPYRIDIN-2-YL)-4,5-DIHYDRO-1 H-PYRAZOLE-5- CARBOXYLATE FMC Corporation (US) 2024-12-11 — — EP disclosed
EP-4472964-A1 METHODS FOR THE PREPARATION OF ETHYL 3-BROMO-1-(3-CHLOROPYRIDIN-2-YL)-4,5-DIHYDRO-1 H-PYRAZOLE-5- CARBOXYLATE FMC Corporation (US) 2024-12-11 — — EP disclosed
CN-115636825-B Preparation method of intermediate oxazinone and application of intermediate oxazinone in preparation of bisamide pesticide 山东省农药科学研究院 2024-06-25 — — CN disclosed
CN-115745956-B Synthesis method of 3-bromo-1- (3-chloro-2-pyridyl) -1 hydrogen-pyrazole-5-formic acid 浙江新安化工集团股份有限公司 2024-04-12 — — CN disclosed
CN-117820294-A Preparation method of 3-bromo-1- (3-chloro-2-pyridyl) -1-H-pyrazole-5-formic acid compound 重庆华歌生物化学有限公司 2024-04-05 — — CN disclosed
US-20240067624-A1 PROCESS FOR PREPARATION OF INSECTICIDAL ANTHRANILAMIDES UPL LTD (IN) 2024-02-29 — — US disclosed
CN-100349890-C Quinazolinone (di) ones for controlling invertebrate pests DU PONT (US) 2007-11-21 — — CN disclosed
CN-1307161-C Substituted dihydro-3-halo-1H-pyrazole-5-carboxylic acid esters, their preparation and use DU PONT (US) 2007-03-28 — — CN disclosed
WO-2006102025-A1 CONVERSION OF 2-PYRAZOLINES TO PYRAZOLES USING BROMINE E.I. DUPONT DE NEMOURS AND COMPANY (US) 2006-09-28 — — WO disclosed
CN-1620450-A Quinazolinone (di) ones for controlling invertebrate pests DU PONT (US) 2005-05-25 — — CN disclosed
CN-1541206-A Substituted dihydro 3-hylo-1H-pyrazoloe-5-carboxylates their prepn. and use ��Ļ���Ű˾ 2004-10-27 — — CN disclosed
EP-1427285-A1 ANTHRANILAMIDE ARTHROPODICIDE TREATMENT E. I. du Pont de Nemours and Company (US) 2004-06-16 — — EP disclosed
WO-2003024222-A1 ANTHRANILAMIDE ARTHROPODICIDE TREATMENT E. I. DU PONT DE NEMOURS AND COMPANY (US) 2003-03-27 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240067624-A1 PROCESS FOR PREPARATION OF INSECTICIDAL ANTHRANILAMIDES ANTXR2, NAAA, AGPS SMN1; SMN2 2588/4885MALT1 4208/4885TRPA1 1618/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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