Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.38 |
| ▸ | PHGDH | O43175 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.37 |
| ▸ | MYC | P01106 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6909143 | 0.86 | MALT1 (0.43) | MALT1SMN1; SMN2TRPV1TRPA1 | |
| SCHEMBL27121774 | 0.86 | SMN1; SMN2 (0.39) | MALT1SMN1; SMN2HSD11B1TRPV1MYC | |
| SCHEMBL30301254 | 0.86 | MALT1 (0.43) | MALT1SMN1; SMN2TRPV1TRPA1 | |
| SCHEMBL31690628 | 0.85 | MALT1 (0.43) | MALT1SMN1; SMN2TRPV1TRPA1 | |
| SCHEMBL28966441 | 0.85 | MALT1 (0.43) | MALT1SMN1; SMN2TRPV1TRPA1 | |
| SCHEMBL29402480 | 0.84 | SMN1; SMN2 (0.43) | MALT1SMN1; SMN2TRPV1PHGDHTRPA1 | |
| SCHEMBL1800944 | 0.84 | SMN1; SMN2 (0.43) | MALT1SMN1; SMN2TRPV1PHGDHTRPA1 | |
| SCHEMBL26192022 | 0.84 | CYP2C19 (0.46) | MALT1SMN1; SMN2HSD11B1 | |
| SCHEMBL28329940 | 0.78 | MALT1 (0.43) | MALT1SMN1; SMN2TRPV1TRPA1 | |
| SCHEMBL29139410 | 0.77 | MALT1 (0.37) | MALT1SMN1; SMN2TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8217179-B2 | Preparation method of phenylcarboxamides | SINOCHEM CORPORATION (CN) | 2012-07-10 | — | — | US | disclosed |
| US-20100317864-A1 | Preparation Method of Phenylcarboxamides | SHENYANG SINOCHEM AGROCHEMICALS R&D CO., LTD. (CN) | 2010-12-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100317864-A1 | Preparation Method of Phenylcarboxamides | HDHD5, AADAC, ABHD5 | MALT1 3239/4885SMN1; SMN2 4421/4885HSD11B1 888/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.