SCHEMBL18009559

SCHEMBL18009559

CC1=Cc2cc3c(cc2C1)CC(C)(C)C3

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21776970 0.75 PTGS2 (0.40)
SCHEMBL5716873 0.75 TSHR (0.33)
SCHEMBL29534955 0.75 NPC1 (0.31)
SCHEMBL2782866 0.72 NPC1 (0.34)
SCHEMBL25748393 0.71
SCHEMBL4406365 0.71 RARB (0.34)
SCHEMBL1818812 0.71
SCHEMBL30175873 0.71
SCHEMBL22816916 0.68
SCHEMBL22815692 0.68 HRH4 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109312015-A Tetrahydroindacenyl catalyst compositions, catalyst systems, and methods of use thereof 埃克森美孚化学专利公司 2019-02-05 CN claimed
CN-114685703-A Catalyst compositions comprising fluorinated supports and methods of use thereof 埃克森美孚化学专利公司 2022-07-01 CN disclosed
US-10717790-B2 Catalyst composition comprising fluorided support and processes for use thereof EXXONMOBIL CHEMICAL PATENTS INC. (US) 2020-07-21 US disclosed
EP-3286231-B1 CATALYST COMPOSITION COMPRISING FLUORIDED SUPPORT AND PROCESSES FOR USE THEREOF EXXONMOBIL CHEMICAL PATENTS INC (US) 2019-10-09 EP disclosed
US-20180072823-A1 Catalyst Composition Comprising Fluorided Support and Processes for Use Thereof EXXONMOBIL CHEMICAL PATENTS INC. 2018-03-15 US disclosed
EP-3286231-A1 CATALYST COMPOSITION COMPRISING FLUORIDED SUPPORT AND PROCESSES FOR USE THEREOF ExxonMobil Chemical Patents Inc. (US) 2018-02-28 EP disclosed
US-9796795-B2 Tetrahydroindacenyl catalyst composition, catalyst system, and processes for use thereof EXXONMOBIL CHEMICAL PATENTS INC. (US) 2017-10-24 US disclosed
WO-2016171808-A1 CATALYST COMPOSITION COMPRISING FLUORIDED SUPPORT AND PROCESSES FOR USE THEREOF EXXONMOBIL CHEMICAL PATENTS INC. (US) 2016-10-27 WO disclosed
US-20160244535-A1 Tetrahydroindacenyl Catalyst Composition, Catalyst System, and Processes for Use Thereof EXXONMOBIL CHEMICAL PATENTS INC. 2016-08-25 US disclosed