SCHEMBL5716873

SCHEMBL5716873

CC1=Cc2cc3c(cc2C1)CCCC3

nearest known ligand 0.33

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.33
CDC25B P30305 1/20 0.31
KDM4E B2RXH2 1/20 0.30
MEN1 O00255 1/20 0.30
ALDH1A1 P00352 1/20 0.30
GAA P10253 1/20 0.30
MAPT P10636 1/20 0.30
PKM P14618 1/20 0.30
KMT2A Q03164 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL413201 0.96 NPC1 (0.31)
SCHEMBL29534955 0.96 NPC1 (0.31)
SCHEMBL409885 0.82
SCHEMBL2865299 0.76 DRD2 (0.30)
SCHEMBL18009559 0.75
SCHEMBL2782866 0.75 NPC1 (0.34) MAPT
SCHEMBL25748393 0.74
SCHEMBL6889520 0.74 CDC25B (0.31) TSHRCDC25BKDM4EMEN1ALDH1A1
SCHEMBL28911482 0.72 CDC25B (0.30) CDC25B
SCHEMBL28911503 0.72 CDC25B (0.30) CDC25B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3553093-B1 TRANSITION METAL COMPOUND FOR OLEFIN POLYMERIZATION CATALYST AND OLEFIN POLYMERIZATION CATALYST COMPRISING THE SAME HANWHA CHEMICAL CORP (KR) 2026-05-06 EP disclosed
CN-110036041-B Transition metal compound for olefin polymerization catalyst, olefin polymerization catalyst comprising same, and polyolefin polymerized using same 韩华化学株式会社 2022-10-14 CN disclosed
US-11236186-B2 Transition metal compound for olefin polymerization catalyst, olefin polymerization catalyst comprising same, and polyolefin polymerized using same HANWHA CHEMICAL CORPORATION (KR) 2022-02-01 US disclosed
EP-3553093-A1 TRANSITION METAL COMPOUND FOR OLEFIN POLYMERIZATION CATALYST, OLEFIN POLYMERIZATION CATALYST COMPRISING SAME, AND POLYOLEFIN POLYMERIZED USING SAME Hanwha Chemical Corporation (KR) 2019-10-16 EP disclosed
US-20190309110-A1 TRANSITION METAL COMPOUND FOR OLEFIN POLYMERIZATION CATALYST, OLEFIN POLYMERIZATION CATALYST COMPRISING SAME, AND POLYOLEFIN POLYMERIZED USING SAME HANWHA CHEMICAL CORPORATION (KR) 2019-10-10 US disclosed
EP-1337501-B1 PROCESS FOR PREPARING 1-INDANONES AKZO NOBEL NV (NL) 2006-12-20 EP disclosed
EP-1337501-A1 PROCESS FOR PREPARING 1-INDANONES Akzo Nobel N.V. (NL) 2003-08-27 EP disclosed
US-6548710-B2 Reacting ketone compound with chlorinating agent, followed by reaction with a friedel-crafts catalyst to produce 1-indanone compound AKZO NOBEL N.V. (NL) 2003-04-15 US disclosed
US-20020077507-A1 Process for preparing 1-indanones AKZO NOBEL N.V. (NL) 2002-06-20 US disclosed
WO-2002036537-A1 PROCESS FOR PREPARING 1-INDANONES AKZO NOBEL N.V. (NL) 2002-05-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11236186-B2 Transition metal compound for olefin polymerization catalyst, olefin polymerization catalyst comprising same, and polyolefin polymerized using same ALOX12, PPOX, ODC1 TSHR 4811/4885CDC25B 1659/4885KDM4E 3840/4885
US-20190309110-A1 TRANSITION METAL COMPOUND FOR OLEFIN POLYMERIZATION CATALYST, OLEFIN POLYMERIZATION CATALYST COMPRISING SAME, AND POLYOLEFIN POLYMERIZED USING SAME ALOX12, PPOX, ODC1 TSHR 4811/4885CDC25B 1659/4885KDM4E 3840/4885
US-20020077507-A1 Process for preparing 1-indanones CYP1A1, CYP2F1, CYP1B1 TSHR 2087/4885CDC25B 645/4885KDM4E 1077/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.