Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1979983 | 0.87 | TSHR (0.47) | GSK3BPPARGPPARASCN9ANPC1 | |
| SCHEMBL3665372 | 0.77 | PPARG (0.35) | PPARGPPARASCN9ASLC6A2SLC6A4 | |
| SCHEMBL19270341 | 0.72 | TSHR (0.50) | PPARGPPARATSHRL3MBTL1 | |
| SCHEMBL3689235 | 0.72 | TSHR (0.47) | GSK3BPPARGPPARASCN9AS1PR1 | |
| SCHEMBL3680890 | 0.72 | TSHR (0.47) | GSK3BPPARGPPARASCN9AS1PR1 | |
| SCHEMBL3724306 | 0.71 | BRD4 (0.36) | GSK3BCA1CA2ALDH1A1MAPK1 | |
| SCHEMBL15867663 | 0.71 | CNR1 (0.45) | NPC1RAB9AHIF1AFAAHMEN1 | |
| SCHEMBL21610394 | 0.69 | MAOB (0.43) | PPARGPPARASCN9ASLC6A2SLC6A4 | |
| SCHEMBL21602986 | 0.69 | TAAR1 (0.42) | PPARGPPARASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL12896367 | 0.69 | TEAD1 (0.44) | PPARGPPARACA1CA2SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160242416-A1 | FUNGICIDAL ISOXAZOLINE CARBINOLS | DU PONT (US) | 2016-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160242416-A1 | FUNGICIDAL ISOXAZOLINE CARBINOLS | CYP1B1, CHRM1, CYP1A1 | GSK3B 220/4885PPARG 3772/4885PPARA 3472/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.