Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 18/20 | 1.00 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.55 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.55 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.55 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.55 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.55 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL18010404 | 0.99 | HTR7 (1.00) | HTR7PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL18010366 | 0.99 | HTR7 (1.00) | HTR7PSEN1PSEN2APH1BNCSTN | |
| Hydrochloric Acid SCHEMBL18010424 | 0.97 | HTR7 (1.00) | HTR7PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL9397196 | 0.87 | HTR7 (0.76) | HTR7PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL154233 | 0.87 | HTR7 (0.76) | HTR7PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL9397231 | 0.87 | HTR7 (0.76) | HTR7PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL9398280 | 0.86 | HTR7 (0.74) | HTR7PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL18010436 | 0.84 | HTR7 (1.00) | HTR7 | |
| SCHEMBL18010422 | 0.83 | HTR7 (1.00) | HTR7 | |
| SCHEMBL9905074 | 0.82 | HTR7 (0.69) | HTR7PSEN1PSEN2APH1BNCSTN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160244408-A1 | CARBAZOLE DERIVATIVES ACTING ON 5-HT7 RECEPTOR | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2016-08-25 | — | — | US | claimed |
| US-9663464-B2 | Carbazole derivatives acting on 5-HT7 receptor | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2017-05-30 | — | — | US | disclosed |
| US-9663464-B2 | Carbazole derivatives acting on 5-HT7 receptor | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2017-05-30 | — | — | US | disclosed |
| US-9663464-B2 | Carbazole derivatives acting on 5-HT7 receptor | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2017-05-30 | — | — | US | disclosed |
| US-20160244408-A1 | CARBAZOLE DERIVATIVES ACTING ON 5-HT7 RECEPTOR | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2016-08-25 | — | — | US | disclosed |
| US-20160244408-A1 | CARBAZOLE DERIVATIVES ACTING ON 5-HT7 RECEPTOR | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2016-08-25 | — | — | US | disclosed |
| US-20160244408-A1 | CARBAZOLE DERIVATIVES ACTING ON 5-HT7 RECEPTOR | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2016-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160244408-A1 | CARBAZOLE DERIVATIVES ACTING ON 5-HT7 RECEPTOR | HTR7, HTR3A, HTR3B | HTR7 1/4885PSEN1 1717/4885PSEN2 1971/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.