SCHEMBL18010385

SCHEMBL18010385

O=C(CCCCN1CCC(c2ccccc2)CC1)n1c2ccccc2c2ccccc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HTR7 P34969 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18028064 0.99 HTR7 (1.00) HTR7
Hydrochloric Acid SCHEMBL18010379 0.99 HTR7 (1.00) HTR7
SCHEMBL18028061 0.99 HTR7 (1.00) HTR7
SCHEMBL18010442 0.99 HTR7 (1.00) HTR7
Hydrochloric Acid SCHEMBL18010425 0.98 HTR7 (1.00) HTR7
SCHEMBL18010413 0.85 HTR7 (1.00) HTR7
Hydrochloric Acid SCHEMBL18010363 0.84 HTR7 (0.98) HTR7
SCHEMBL18010350 0.84 HTR7 (1.00) HTR7
SCHEMBL18010408 0.83 HTR7 (1.00) HTR7
SCHEMBL18010432 0.83 HTR7 (1.00) HTR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160244408-A1 CARBAZOLE DERIVATIVES ACTING ON 5-HT7 RECEPTOR KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2016-08-25 US claimed
US-9663464-B2 Carbazole derivatives acting on 5-HT7 receptor KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2017-05-30 US disclosed
US-9663464-B2 Carbazole derivatives acting on 5-HT7 receptor KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2017-05-30 US disclosed
US-9663464-B2 Carbazole derivatives acting on 5-HT7 receptor KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2017-05-30 US disclosed
US-20160244408-A1 CARBAZOLE DERIVATIVES ACTING ON 5-HT7 RECEPTOR KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2016-08-25 US disclosed
US-20160244408-A1 CARBAZOLE DERIVATIVES ACTING ON 5-HT7 RECEPTOR KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2016-08-25 US disclosed
US-20160244408-A1 CARBAZOLE DERIVATIVES ACTING ON 5-HT7 RECEPTOR KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2016-08-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160244408-A1 CARBAZOLE DERIVATIVES ACTING ON 5-HT7 RECEPTOR HTR7, HTR3A, HTR3B HTR7 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.