SCHEMBL18010455

SCHEMBL18010455

OC(CC12CC3CC(CC(C3)C1)C2)C12CC3CC(CC(C3)C1)C2

nearest known ligand 0.46

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.46
MEN1 O00255 2/20 0.46
GRIN2D O15399 4/20 0.41
GRIN3B O60391 4/20 0.41
GRIN1 Q05586 4/20 0.41
GRIN2A Q12879 4/20 0.41
GRIN2B Q13224 4/20 0.41
GRIN2C Q14957 4/20 0.41
GRIN3A Q8TCU5 4/20 0.41
SLC22A2 O15244 1/20 0.38
SLC47A1 Q96FL8 1/20 0.38
ALDH1A1 P00352 3/20 0.37
MAPT P10636 1/20 0.37
TSHR P16473 1/20 0.36
CA12 O43570 1/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
CA9 Q16790 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3813603 0.76 KMT2A (0.48) KMT2AMEN1GRIN2DGRIN3BGRIN1
SCHEMBL2965277 0.74 KMT2A (0.47) KMT2AMEN1SLC22A2SLC47A1ALDH1A1
SCHEMBL7445771 0.74 MEN1 (0.47) KMT2AMEN1GRIN2DGRIN3BGRIN1
SCHEMBL7442387 0.74 MEN1 (0.47) KMT2AMEN1GRIN2DGRIN3BGRIN1
SCHEMBL3180369 0.74 MEN1 (0.47) KMT2AMEN1GRIN2DGRIN3BGRIN1
SCHEMBL7714550 0.73 GRIN2D (0.41) KMT2AMEN1GRIN2DGRIN3BGRIN1
SCHEMBL28136762 0.73 KMT2A (0.44) KMT2AMEN1GRIN2DGRIN3BGRIN1
Ammonia Solution, Strong SCHEMBL11633437 0.73 KMT2A (0.46) KMT2AMEN1SLC22A2SLC47A1ALDH1A1
SCHEMBL14306348 0.70 SLC22A2 (0.44) KMT2AMEN1GRIN2DGRIN3BGRIN1
SCHEMBL14086753 0.70 SMN1; SMN2 (0.46) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160244791-A1 METHODS AND ENZYMES FOR PRODUCING HYDROXYMETHYLFURFURAL UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED 2016-08-25 US disclosed