Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.39 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.32 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.32 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7442387 | 1.00 | MEN1 (0.47) | MEN1KMT2ASLC22A2SLC47A1MAPT | |
| SCHEMBL3813603 | 0.78 | KMT2A (0.48) | MEN1KMT2ASLC22A2SLC47A1MAPT | |
| SCHEMBL2965277 | 0.76 | KMT2A (0.47) | MEN1KMT2ASLC22A2SLC47A1MAPT | |
| SCHEMBL3180369 | 0.76 | MEN1 (0.47) | MEN1KMT2ASLC22A2SLC47A1MAPT | |
| Ammonia Solution, Strong SCHEMBL11633437 | 0.74 | KMT2A (0.46) | MEN1KMT2ASLC22A2SLC47A1MAPT | |
| SCHEMBL18010455 | 0.74 | KMT2A (0.46) | MEN1KMT2ASLC22A2SLC47A1MAPT | |
| SCHEMBL14306348 | 0.72 | SLC22A2 (0.44) | MEN1KMT2ASLC22A2SLC47A1MAPT | |
| SCHEMBL18135491 | 0.71 | MEN1 (0.43) | MEN1KMT2ASLC22A2SLC47A1SMN1; SMN2 | |
| SCHEMBL27694055 | 0.71 | ALDH1A1 (0.39) | MEN1KMT2ASLC22A2SLC47A1MAPT | |
| SCHEMBL4027679 | 0.71 | SLC22A2 (0.48) | MEN1KMT2ASLC22A2SLC47A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996038435-A1 | DOPAMINE AGONISTS | ABBOTT LABORATORIES (US) | 1996-12-05 | — | — | WO | disclosed |
| EP-0474767-B1 | DOPAMINE AGONISTS | ABBOTT LAB (US) | 1996-02-21 | — | — | EP | disclosed |
| EP-0474767-A4 | DOPAMINE AGONISTS | — | 1992-07-08 | — | — | EP | disclosed |
| EP-0474767-A1 | DOPAMINE AGONISTS. | ABBOTT LAB (US) | 1992-03-18 | — | — | EP | disclosed |
| WO-1990015056-A1 | DOPAMINE AGONISTS | ABBOTT LABORATORIES (US) | 1990-12-13 | — | — | WO | disclosed |