Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 2/20 | 0.49 |
| ▸ | ACE | P12821 | 1/20 | 0.49 |
| ▸ | SCN4A | P35499 | 4/20 | 0.49 |
| ▸ | ALPI | P09923 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | XIAP | P98170 | 1/20 | 0.40 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7444134 | 0.80 | GPR139 (0.49) | SCN4A | |
| SCHEMBL11941176 | 0.79 | ACE (0.54) | MMEACE | |
| SCHEMBL27875411 | 0.79 | EPHX1 (0.54) | MMEACEPKMMTNR1AMTNR1B | |
| SCHEMBL10438808 | 0.78 | MME (0.49) | MMEACE | |
| SCHEMBL4523623 | 0.76 | SCN4A (0.58) | SCN4A | |
| SCHEMBL16133830 | 0.76 | SCN4A (0.58) | SCN4A | |
| SCHEMBL27214040 | 0.76 | SCN4A (0.46) | SCN4A | |
| SCHEMBL859558 | 0.75 | ALPI (0.55) | MMEACEALPIPKMPTGS1 | |
| SCHEMBL1337302 | 0.75 | ALPI (0.55) | MMEACEALPIPKMPTGS1 | |
| SCHEMBL1256892 | 0.75 | ALPI (0.55) | MMEACEALPIPKMPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016124939-A1 | AUTOTAXIN INHIBITORY COMPOUNDS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2016-08-11 | — | — | WO | disclosed |