Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.49 |
| ▸ | SCN4A | P35499 | 2/20 | 0.44 |
| ▸ | ANPEP | P15144 | 2/20 | 0.44 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18012500 | 0.80 | MME (0.49) | SCN4A | |
| SCHEMBL7611296 | 0.80 | KIF11 (0.50) | — | |
| SCHEMBL1192897 | 0.80 | KIF11 (0.50) | — | |
| SCHEMBL29089227 | 0.79 | GPR139 (0.56) | GPR139KMT2ATDP1L3MBTL1CES2 | |
| SCHEMBL10358939 | 0.76 | GABBR2 (0.54) | GPR139KMT2ATDP1L3MBTL1LMNA | |
| SCHEMBL6057191 | 0.76 | GPR139 (0.53) | GPR139KMT2ATDP1CES2LMNA | |
| SCHEMBL27214040 | 0.74 | SCN4A (0.46) | SCN4A | |
| SCHEMBL18759308 | 0.74 | GPR139 (0.51) | GPR139KMT2ATDP1CES2LMNA | |
| Ammonia Solution, Strong SCHEMBL7436224 | 0.74 | GPR139 (0.51) | GPR139KMT2ATDP1CES2LMNA | |
| SCHEMBL23154643 | 0.73 | KIF11 (0.51) | GPR139KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640594-A1 | Hydantoin derivative as metalloprotease inhibitor | FUJIREBIO INC. (JP) | 1995-03-01 | — | — | EP | disclosed |