Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K11 | Q16584 | 5/20 | 0.46 |
| ▸ | TNIK | Q9UKE5 | 9/20 | 0.41 |
| ▸ | IGF1R | P08069 | 2/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | WDR5 | P61964 | 1/20 | 0.37 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1799494 | 0.91 | TNIK (0.39) | MAP3K11TNIKNTRK1 | |
| SCHEMBL1798276 | 0.90 | NTRK1 (0.47) | MAP3K11ROCK1WDR5NTRK1 | |
| SCHEMBL1800577 | 0.84 | MAP3K11 (0.55) | MAP3K11TNIKIGF1R | |
| SCHEMBL1801625 | 0.84 | AXL (0.40) | TNIKROCK1NTRK1 | |
| SCHEMBL4403894 | 0.82 | MAP4K1 (0.55) | MAP3K11TNIK | |
| SCHEMBL1801553 | 0.82 | MAP3K11 (0.45) | MAP3K11TNIKIGF1RROCK1CYP3A4 | |
| SCHEMBL1801257 | 0.81 | MAP3K11 (0.46) | MAP3K11TNIKIGF1RROCK1CYP3A4 | |
| SCHEMBL1799327 | 0.80 | MAP3K11 (0.44) | MAP3K11TNIKIGF1RROCK1CYP3A4 | |
| SCHEMBL1798971 | 0.80 | MAP4K1 (0.43) | MAP3K11TNIKIGF1RROCK1CYP3A4 | |
| SCHEMBL1801623 | 0.79 | MAP3K11 (0.44) | MAP3K11TNIKIGF1RROCK1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7951802-B2 | Use of 7-azaindoles in the inhibition of c-Jun N-terminal kinase | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2011-05-31 | — | — | US | disclosed |