⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL182137 | 0.72 | — | — | |
| SCHEMBL871099 | 0.68 | GAA (0.55) | — | |
| SCHEMBL8942627 | 0.68 | GAA (0.55) | — | |
| SCHEMBL88894 | 0.68 | GAA (0.55) | — | |
| SCHEMBL56313 | 0.68 | GAA (0.55) | — | |
| SCHEMBL182729 | 0.67 | ITGB2 (0.35) | — | |
| SCHEMBL182313 | 0.67 | SMN1; SMN2 (0.38) | — | |
| SCHEMBL5759505 | 0.67 | ALDH1A1 (0.44) | — | |
| Hydrochloric Acid SCHEMBL27373511 | 0.67 | GAA (0.53) | — | |
| SCHEMBL11342856 | 0.65 | ALDH1A1 (0.61) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119768404-A | Heteroaryl substituted pyridopyrrolidone derivatives, pharmaceutical compositions and uses thereof | 上海海雁医药科技有限公司 | 2025-04-04 | — | — | CN | disclosed |
| CN-118373808-A | Substituted pyrimidine or pyridine amine derivatives, compositions thereof and pharmaceutical use thereof | 上海海雁医药科技有限公司 | 2024-07-23 | — | — | CN | disclosed |
| CN-113748110-B | Substituted pyrimidine or pyridine amine derivatives, compositions thereof and pharmaceutical use thereof | 上海海雁医药科技有限公司 | 2024-05-14 | — | — | CN | disclosed |
| CN-116761609-A | Substituted pyrazolo [1,5-a ] pyrimidin-7-amine derivatives, compositions thereof and pharmaceutical uses thereof | 上海海雁医药科技有限公司 | 2023-09-15 | — | — | CN | disclosed |
| CN-114085220-B | Substituted morpholine-4-carboxylic acid ester derivatives, compositions and pharmaceutical uses thereof | 上海海雁医药科技有限公司 | 2023-06-16 | — | — | CN | disclosed |
| CN-113429410-B | Polyheterocyclic substituted pyrimidine or pyridylamine derivatives, compositions and medical uses thereof | 上海海雁医药科技有限公司 | 2022-10-04 | — | — | CN | disclosed |
| CN-114085220-A | Substituted morpholine-4-carboxylic ester derivatives, their compositions and their medical use | 上海海雁医药科技有限公司 | 2022-02-25 | — | — | CN | disclosed |
| US-10815197-B2 | N-sulfonyl benzamides as voltage-gated sodium channel inhibitors | SHANGHAI HAIYAN PHARMACEUTICAL TECHNOLOGY CO., LTD. (CN) | 2020-10-27 | — | — | US | disclosed |
| US-20190023654-A1 | N-SULFONYL BENZAMIDE DERIVATIVE WITH HETEROCYCLIC SUBSTITUENT, PREPARATION METHOD THEREFOR AND PHARMACEUTICAL APPLICATION THEREOF | YANGTZE RIVER PHARMACEUTICAL GROUP CO., LTD. (CN) | 2019-01-24 | — | — | US | disclosed |
| WO-2016124139-A1 | HETEROCYCLIC-SUBSTITUTED N-SULFONYLBENZAMIDE DERIVATIVES, PREPARATION METHOD FOR DERIVATIVES, AND PHARMACEUTICAL USE OF DERIVATIVES | 上海海雁医药科技有限公司 | 2016-08-11 | — | — | WO | disclosed |