Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.55 |
| ▸ | HTR2C | P28335 | 6/20 | 0.50 |
| ▸ | HTR2B | P41595 | 6/20 | 0.50 |
| ▸ | HTR2A | P28223 | 4/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3689578 | 0.76 | CYP3A4 (0.35) | KDM1AHTR2CHTR2BCYP3A4ALDH1A1 | |
| SCHEMBL3682416 | 0.76 | CYP3A4 (0.35) | KDM1AHTR2CHTR2BCYP3A4ALDH1A1 | |
| SCHEMBL3684020 | 0.76 | CYP3A4 (0.35) | KDM1AHTR2CHTR2BCYP3A4ALDH1A1 | |
| SCHEMBL13100735 | 0.76 | HTR2A (0.49) | HTR2CHTR2BHTR2ASLC6A2SLC6A3 | |
| SCHEMBL1802723 | 0.76 | CYP3A4 (0.35) | KDM1AHTR2CHTR2BCYP3A4ALDH1A1 | |
| SCHEMBL2343607 | 0.76 | HTR2A (0.49) | HTR2CHTR2BHTR2ASLC6A2SLC6A3 | |
| SCHEMBL1085944 | 0.76 | CYP3A4 (0.35) | KDM1AHTR2CHTR2BCYP3A4ALDH1A1 | |
| SCHEMBL31172423 | 0.72 | KDM1A (0.61) | KDM1AHTR2CHTR2BHTR2ASLC6A2 | |
| SCHEMBL15096162 | 0.72 | KDM1A (0.96) | KDM1AHTR2CHTR2BHTR2ASLC6A2 | |
| SCHEMBL12876076 | 0.72 | KDM1A (0.61) | KDM1AHTR2CHTR2BHTR2ASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7951752-B2 | O-cyclopropyl-carboxanilides and their use as fungicides | SYNGENTA CROP PROTECTION, INC. (US) | 2011-05-31 | — | — | US | disclosed |
| US-7820830-B2 | Process for the production of carboxanilides | SYNGENTA CROP PROTECTION, INC. (US) | 2010-10-26 | — | — | US | disclosed |
| US-7737301-B2 | Preparation of 2-bicyclopropyl-2-yl-phenylamine through catalyzing the dehydrochlorination in the presence of a palladium complex; cost efficiency; used as intermediates for the preparation of fungicides | SYNGENTA CROP PROTECTION, INC. (US) | 2010-06-15 | — | — | US | disclosed |
| US-20090221855-A1 | PROCESS FOR THE PRODUCTION OF ANILINES | SYNGENTA CROP PROTECTION, INC. (US) | 2009-09-03 | — | — | US | disclosed |
| EP-1951677-B1 | PROCESS FOR THE PRODUCTION OF CARBOXANILIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2009-09-02 | — | — | EP | disclosed |
| US-20090197925-A1 | O-CYCLOPROPYL-CARBOXANILIDES AND THEIR USE | SYNGENTA CROP PROTECTION, INC. (US) | 2009-08-06 | — | — | US | disclosed |
| EP-1931618-B1 | PROCESS FOR THE PRODUCTION OF ANILINES | SYNGENTA PARTICIPATIONS AG (CH) | 2009-08-05 | — | — | EP | disclosed |
| US-20090177011-A1 | PROCESS FOR THE PRODUCTION OF ANILINES | SYNGENTA CROP PROTECTION, INC. (US) | 2009-07-09 | — | — | US | disclosed |
| US-20080262242-A1 | Process For the Production of Carboxanilides | SYNGENTA CROP PROTECTION, INC. (US) | 2008-10-23 | — | — | US | disclosed |
| EP-1951677-A1 | PROCESS FOR THE PRODUCTION OF CARBOXANILIDES | Syngeta Participations AG (CH) | 2008-08-06 | — | — | EP | disclosed |
| EP-1931618-A1 | PROCESS FOR THE PRODUCTION OF ANILINES | Syngeta Participations AG (CH) | 2008-06-18 | — | — | EP | disclosed |
| EP-1829865-A2 | Chemical compounds | Syngeta Participations AG (CH) | 2007-09-05 | — | — | EP | disclosed |
| EP-1819660-A1 | PROCESS FOR THE PRODUCTION OF ANILINES | Syngeta Participations AG (CH) | 2007-08-22 | — | — | EP | disclosed |
| EP-1480955-B1 | O-CYCLOPROPYL-CARBOXANILIDES AND THEIR USE AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2007-06-27 | — | — | EP | disclosed |
| WO-2007057140-A1 | PROCESS FOR THE PRODUCTION OF CARBOXANILIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2007-05-24 | — | — | WO | disclosed |
| WO-2007025693-A1 | PROCESS FOR THE PRODUCTION OF ANILINES | SYNGENTA PARTICIPATIONS AG (CH) | 2007-03-08 | — | — | WO | disclosed |
| WO-2006061226-A1 | PROCESS FOR THE PRODUCTION OF ANILINES | SYNGENTA PARTICIPATIONS AG (CH) | 2006-06-15 | — | — | WO | disclosed |
| US-20050221989-A1 | O-cyclopropyl-carboxanilides and their use as fungicides | SYNGENTA CROP PROTECTION, INC. | 2005-10-06 | — | — | US | disclosed |
| EP-1480955-A1 | O-CYCLOPROPYL-CARBOXANILIDES AND THEIR USE AS FUNGICIDES | Syngenta Participations AG (CH) | 2004-12-01 | — | — | EP | disclosed |
| WO-2003074491-A1 | O-CYCLOPROPYL-CARBOXANILIDES AND THEIR USE AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2003-09-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090221855-A1 | PROCESS FOR THE PRODUCTION OF ANILINES | CBR3, C1S, C9 | KDM1A 967/4885HTR2C 2224/4885HTR2B 1717/4885 |
| US-20050221989-A1 | O-cyclopropyl-carboxanilides and their use as fungicides | CBR3, CBR1, CYP2E1 | KDM1A 1882/4885HTR2C 844/4885HTR2B 792/4885 |
| US-20090197925-A1 | O-CYCLOPROPYL-CARBOXANILIDES AND THEIR USE | CBR3, CBR1, CYC1 | KDM1A 3913/4885HTR2C 971/4885HTR2B 1014/4885 |
| US-20090177011-A1 | PROCESS FOR THE PRODUCTION OF ANILINES | CYP1A1, AOC3, CYP1B1 | KDM1A 162/4885HTR2C 1487/4885HTR2B 1943/4885 |
| US-20080262242-A1 | Process For the Production of Carboxanilides | FGFR2, FGFR4, CCKBR | KDM1A 1268/4885HTR2C 1605/4885HTR2B 1057/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.