Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 5/20 | 0.49 |
| ▸ | HTR2C | P28335 | 5/20 | 0.49 |
| ▸ | HTR2B | P41595 | 5/20 | 0.49 |
| ▸ | DPP4 | P27487 | 2/20 | 0.46 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13100735 | 1.00 | HTR2A (0.49) | HTR2AHTR2CHTR2BDPP4SLC9A1 | |
| SCHEMBL18611826 | 0.79 | HTR2A (0.45) | HTR2AHTR2CHTR2BDPP4SLC9A1 | |
| SCHEMBL1085944 | 0.76 | CYP3A4 (0.35) | HTR2CHTR2BSMN1; SMN2 | |
| SCHEMBL3684020 | 0.76 | CYP3A4 (0.35) | HTR2CHTR2BSMN1; SMN2 | |
| SCHEMBL1801330 | 0.76 | KDM1A (0.55) | HTR2AHTR2CHTR2BSLC6A3SLC6A2 | |
| SCHEMBL1802723 | 0.76 | CYP3A4 (0.35) | HTR2CHTR2BSMN1; SMN2 | |
| SCHEMBL3689578 | 0.76 | CYP3A4 (0.35) | HTR2CHTR2BSMN1; SMN2 | |
| SCHEMBL3682416 | 0.76 | CYP3A4 (0.35) | HTR2CHTR2BSMN1; SMN2 | |
| SCHEMBL6568329 | 0.74 | DPP4 (0.52) | HTR2AHTR2CHTR2BDPP4SLC9A1 | |
| SCHEMBL6568327 | 0.74 | DPP4 (0.52) | HTR2AHTR2CHTR2BDPP4SLC9A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8426646-B2 | Process for the production of amines | SYNGENTA CROP PROTECTION LLC (US) | 2013-04-23 | — | — | US | disclosed |
| EP-2176212-B1 | PROCESS FOR THE PRODUCTION OF AMINES | SYNGENTA PARTICIPATIONS AG (CH) | 2011-08-31 | — | — | EP | disclosed |
| US-7820830-B2 | Process for the production of carboxanilides | SYNGENTA CROP PROTECTION, INC. (US) | 2010-10-26 | — | — | US | disclosed |
| US-20100256417-A1 | PROCESS FOR THE PRODUCTION OF AROMATIC AMINDES IN THE PRESENCE OF A PALLADIUM COMPLEX COMPRISING A FERROCENYL BIPHOSPHINE LIGAND | SYNGENTA CROP PROTECTION, INC. (US) | 2010-10-07 | — | — | US | disclosed |
| US-20100228055-A1 | PROCESS FOR THE PRODUCTION OF AMINES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-09-09 | — | — | US | disclosed |
| US-7737301-B2 | Preparation of 2-bicyclopropyl-2-yl-phenylamine through catalyzing the dehydrochlorination in the presence of a palladium complex; cost efficiency; used as intermediates for the preparation of fungicides | SYNGENTA CROP PROTECTION, INC. (US) | 2010-06-15 | — | — | US | disclosed |
| EP-2176212-A1 | PROCESS FOR THE PRODUCTION OF AMINES | Syngenta Participations AG (CH) | 2010-04-21 | — | — | EP | disclosed |
| US-20090221855-A1 | PROCESS FOR THE PRODUCTION OF ANILINES | SYNGENTA CROP PROTECTION, INC. (US) | 2009-09-03 | — | — | US | disclosed |
| EP-1951677-B1 | PROCESS FOR THE PRODUCTION OF CARBOXANILIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2009-09-02 | — | — | EP | disclosed |
| EP-1931618-B1 | PROCESS FOR THE PRODUCTION OF ANILINES | SYNGENTA PARTICIPATIONS AG (CH) | 2009-08-05 | — | — | EP | disclosed |
| EP-2066617-A1 | PROCESS FOR THE PRODUCTION OF AROMATIC AMINES IN THE PRESENCE OF A PALLADIUM COMPLEX COMPRISING A FERROCENYL BIPHOSPHINE LIGAND | Syngeta Participations AG (CH) | 2009-06-10 | — | — | EP | disclosed |
| WO-2009007033-A1 | PROCESS FOR THE PRODUCTION OF AMINES | SYNGENTA PARTICIPATIONS AG (CH) | 2009-01-15 | — | — | WO | disclosed |
| EP-2014642-A1 | Process for the production of amines | Syngeta Participations AG (CH) | 2009-01-14 | — | — | EP | disclosed |
| US-20080262242-A1 | Process For the Production of Carboxanilides | SYNGENTA CROP PROTECTION, INC. (US) | 2008-10-23 | — | — | US | disclosed |
| EP-1951677-A1 | PROCESS FOR THE PRODUCTION OF CARBOXANILIDES | Syngeta Participations AG (CH) | 2008-08-06 | — | — | EP | disclosed |
| EP-1931618-A1 | PROCESS FOR THE PRODUCTION OF ANILINES | Syngeta Participations AG (CH) | 2008-06-18 | — | — | EP | disclosed |
| WO-2008017443-A1 | PROCESS FOR THE PRODUCTION OF AROMATIC AMINES IN THE PRESENCE OF A PALLADIUM COMPLEX COMPRISING A FERROCENYL BIPHOSPHINE LIGAND | SYNGENTA PARTICIPATIONS AG (CH) | 2008-02-14 | — | — | WO | disclosed |
| WO-2007057140-A1 | PROCESS FOR THE PRODUCTION OF CARBOXANILIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2007-05-24 | — | — | WO | disclosed |
| WO-2007025693-A1 | PROCESS FOR THE PRODUCTION OF ANILINES | SYNGENTA PARTICIPATIONS AG (CH) | 2007-03-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090221855-A1 | PROCESS FOR THE PRODUCTION OF ANILINES | CBR3, C1S, C9 | HTR2A 2878/4885HTR2C 2224/4885HTR2B 1717/4885 |
| US-20100228055-A1 | PROCESS FOR THE PRODUCTION OF AMINES | AOC1, C5, C1S | HTR2A 2590/4885HTR2C 2296/4885HTR2B 2422/4885 |
| US-20080262242-A1 | Process For the Production of Carboxanilides | FGFR2, FGFR4, CCKBR | HTR2A 2446/4885HTR2C 1605/4885HTR2B 1057/4885 |
| US-20100256417-A1 | PROCESS FOR THE PRODUCTION OF AROMATIC AMINDES IN THE PRESENCE OF A PALLADIUM COMPLEX COMPRISING A FERROCENYL BIPHOSPHINE LIGAND | AOC1, C5, C9 | HTR2A 2084/4885HTR2C 2170/4885HTR2B 1716/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.