Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2609329 | 0.86 | SCN9A (0.56) | SCN9ATRPV3 | |
| SCHEMBL18014759 | 0.85 | CTSS (0.52) | SCN9ATRPV3 | |
| SCHEMBL18014758 | 0.81 | HSD11B1 (0.39) | SCN9ATRPV3 | |
| SCHEMBL27371992 | 0.80 | SCN9A (0.56) | SCN9ATRPV3 | |
| SCHEMBL4838843 | 0.79 | SCN9A (0.62) | SCN9ATRPV3 | |
| SCHEMBL4837484 | 0.77 | SCN9A (0.64) | SCN9ATRPV3 | |
| SCHEMBL14382171 | 0.76 | SCN9A (0.50) | SCN9ATRPV3 | |
| SCHEMBL4831628 | 0.76 | SCN9A (0.62) | SCN9ATRPV3 | |
| SCHEMBL4831553 | 0.76 | SCN9A (0.62) | SCN9ATRPV3 | |
| SCHEMBL4835464 | 0.76 | SCN9A (0.62) | SCN9ATRPV3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160229847-A1 | NOVEL BICYCLIC PYRIDINONES AS GAMMA-SECRETASE MODULATORS | PFIZER (US) | 2016-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160229847-A1 | NOVEL BICYCLIC PYRIDINONES AS GAMMA-SECRETASE MODULATORS | BACE1, BACE2, PSEN2 | SCN9A 939/4885TRPV3 3597/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.