SCHEMBL1801558

SCHEMBL1801558

CCCCCCCCCCCCCCCC(=O)OC[C@H](CO)OP(=O)(O)OC[C@H](N)C(=O)O

nearest known ligand 0.76

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
P2RY10 O00398 11/20 0.70
GPR34 Q9UPC5 7/20 0.70
GPR174 Q9BXC1 7/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1801499 1.00 P2RY10 (0.70) P2RY10GPR34GPR174
SCHEMBL1800150 0.94 P2RY10 (0.73) P2RY10GPR34GPR174
SCHEMBL15928070 0.87 P2RY10 (0.72) P2RY10GPR34GPR174
SCHEMBL15927983 0.87 P2RY10 (0.72) P2RY10GPR34GPR174
SCHEMBL19941696 0.87 P2RY10 (0.72) P2RY10GPR34GPR174
Dexfosfoserine SCHEMBL28465640 0.85 ENPP2 (0.70) P2RY10GPR34GPR174
Dexfosfoserine SCHEMBL28767573 0.85 ENPP2 (0.70) P2RY10GPR34GPR174
1,2-Dipalmitin SCHEMBL21382909 0.85 ENPP2 (0.70) P2RY10GPR34GPR174
Phosphatidyl Serine SCHEMBL24802704 0.85 P2RY10 (0.75) P2RY10GPR34GPR174
SCHEMBL22531350 0.85 P2RY10 (0.75) P2RY10GPR34GPR174

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7202040-B2 Method for screening compounds which change the binding properties of a protein with a ligand TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2007-04-10 US claimed
US-7951548-B2 IL-13 production inhibitor TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2011-05-31 US disclosed
US-20090170116-A1 IL-13 Production Inhibitor TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2009-07-02 US disclosed
EP-1852503-A1 IL-13 PRODUCTION INHIBITOR Takeda Pharmaceutical Company Limited (JP) 2007-11-07 EP disclosed
US-7202040-B2 Method for screening compounds which change the binding properties of a protein with a ligand TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2007-04-10 US disclosed
US-20050154190-A1 Screening method TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2005-07-14 US disclosed
EP-1455186-A1 SCREENING METHOD Takeda Chemical Industries, Ltd. (JP) 2004-09-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050154190-A1 Screening method SLC6A19, SLC1A5, SLC7A1 P2RY10 3424/4885GPR34 429/4885GPR174 2731/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.