Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 2/20 | 0.51 |
| ▸ | LPL | P06858 | 12/20 | 0.41 |
| ▸ | LIPG | Q9Y5X9 | 12/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18015674 | 0.83 | DGAT1 (0.52) | DGAT1LPLLIPGFFAR1USP30 | |
| SCHEMBL21125909 | 0.83 | DGAT1 (0.67) | DGAT1LPLLIPGCA1CA2 | |
| SCHEMBL10455086 | 0.83 | FFAR1 (0.44) | DGAT1LPLLIPGFFAR1CA1 | |
| SCHEMBL18015661 | 0.83 | DGAT1 (0.57) | DGAT1LPLLIPGFFAR1USP30 | |
| SCHEMBL15916971 | 0.82 | DGAT1 (0.53) | DGAT1LPLLIPGCA1CA2 | |
| SCHEMBL19933582 | 0.82 | DGAT1 (0.62) | DGAT1LPLLIPGCA1CA2 | |
| SCHEMBL25100907 | 0.81 | DGAT1 (0.41) | DGAT1LPLLIPGFFAR1 | |
| SCHEMBL20068614 | 0.81 | DGAT1 (0.56) | DGAT1LPLLIPGFFAR1CA1 | |
| SCHEMBL18015315 | 0.80 | DGAT1 (0.46) | DGAT1LPLLIPGFFAR1CA1 | |
| SCHEMBL11911256 | 0.79 | DGAT1 (0.47) | DGAT1LPLLIPGFFAR1USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11024815-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2021-06-01 | — | — | US | disclosed |
| EP-3254317-B1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2019-07-31 | — | — | EP | disclosed |
| US-20180026209-A1 | Metal Complexes | MERCK PATENT GMBH (DE) | 2018-01-25 | — | — | US | disclosed |
| US-20180026209-A1 | Metal Complexes | MERCK PATENT GMBH (DE) | 2018-01-25 | — | — | US | disclosed |
| WO-2016124304-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2016-08-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11024815-B2 | Metal complexes | EXOC4, EXOC3, TIMCC | DGAT1 1835/4885LPL 4682/4885LIPG 4459/4885 |
| US-20180026209-A1 | Metal Complexes | AP3M1, AP2M1, SOD1 | DGAT1 1328/4885LPL 3416/4885LIPG 3693/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.