Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.61 |
| ▸ | AR | P10275 | 5/20 | 0.51 |
| ▸ | USP7 | Q93009 | 1/20 | 0.50 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.47 |
| ▸ | CCNC | P24863 | 4/20 | 0.47 |
| ▸ | CDK8 | P49336 | 4/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.42 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21116103 | 0.87 | TRPA1 (0.60) | TRPA1ARUSP7CREBBPCCNC | |
| SCHEMBL18014698 | 0.85 | TRPA1 (0.61) | TRPA1ARUSP7CREBBPCCNC | |
| SCHEMBL21116102 | 0.85 | TRPA1 (0.57) | TRPA1ARUSP7CREBBPCCNC | |
| SCHEMBL30549500 | 0.79 | TRPA1 (0.64) | TRPA1ARUSP7CREBBPCCNC | |
| Hydrochloric Acid SCHEMBL30549506 | 0.78 | TRPA1 (0.63) | TRPA1ARUSP7CREBBPCCNC | |
| SCHEMBL31378486 | 0.78 | TRPA1 (0.59) | TRPA1ARUSP7CREBBPCCNC | |
| SCHEMBL20132641 | 0.78 | TRPA1 (0.55) | TRPA1ARUSP7CREBBPCCNC | |
| SCHEMBL4662634 | 0.78 | TRPA1 (0.55) | TRPA1ARUSP7CREBBPCCNC | |
| SCHEMBL23638931 | 0.77 | TRPA1 (0.60) | TRPA1ARUSP7CREBBPCCNC | |
| SCHEMBL15334010 | 0.76 | TRPA1 (0.56) | TRPA1ARCREBBPCCNCCDK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160229847-A1 | NOVEL BICYCLIC PYRIDINONES AS GAMMA-SECRETASE MODULATORS | PFIZER (US) | 2016-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160229847-A1 | NOVEL BICYCLIC PYRIDINONES AS GAMMA-SECRETASE MODULATORS | BACE1, BACE2, PSEN2 | TRPA1 3770/4885AR 3436/4885USP7 2217/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.