Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9971231 | 0.86 | — | — | |
| SCHEMBL15976450 | 0.81 | — | — | |
| SCHEMBL23671801 | 0.79 | LMNA (0.54) | LMNACYP2C9 | |
| SCHEMBL23133699 | 0.79 | LMNA (0.54) | LMNACYP2C9 | |
| SCHEMBL23467552 | 0.79 | LMNA (0.54) | LMNACYP2C9 | |
| SCHEMBL23671794 | 0.79 | LMNA (0.54) | LMNACYP2C9 | |
| SCHEMBL10362732 | 0.79 | LMNA (0.54) | LMNACYP2C9 | |
| SCHEMBL8236140 | 0.77 | LMNA (0.41) | LMNACYP2C9 | |
| SCHEMBL15444767 | 0.77 | ALDH1A1 (0.31) | — | |
| SCHEMBL12313390 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012027261-A1 | SULFONYLPIPERAZINE DERIVATIVES THAT INTERACT WITH GLUCOKINASE REGULATORY PROTEIN FOR THE TREATMENT OF DIABETES | AMGEN INC. (US) | 2012-03-01 | — | — | WO | disclosed |