Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 3/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | CDC25B | P30305 | 2/20 | 0.52 |
| ▸ | CDC25A | P30304 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27617414 | 0.87 | AKR1C3 (0.57) | AKR1C3KDM4EHSD17B10MAPTALOX15 | |
| SCHEMBL809324 | 0.86 | AKR1C3 (0.72) | AKR1C3KDM4EHSD17B10MAPTALOX15 | |
| SCHEMBL6056938 | 0.84 | AKR1C3 (0.69) | AKR1C3KDM4EHSD17B10MAPTALOX15 | |
| SCHEMBL6057040 | 0.84 | AKR1C3 (0.69) | AKR1C3KDM4EHSD17B10MAPTALOX15 | |
| SCHEMBL5069965 | 0.83 | MAPT (0.69) | AKR1C3KDM4EHSD17B10MAPTALOX15 | |
| SCHEMBL6056989 | 0.83 | AKR1C3 (0.67) | AKR1C3KDM4EHSD17B10MAPTALOX15 | |
| SCHEMBL78196 | 0.82 | GAA (0.56) | AKR1C3KDM4EHSD17B10MAPTALOX15 | |
| SCHEMBL29557032 | 0.82 | GAA (0.56) | AKR1C3KDM4EHSD17B10MAPTALOX15 | |
| SCHEMBL22938971 | 0.81 | ALDH1A1 (0.59) | AKR1C3KDM4EHSD17B10ALOX15CDC25B | |
| SCHEMBL1650146 | 0.81 | AKR1C3 (0.60) | AKR1C3KDM4EHSD17B10MAPTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150175518-A1 | METAL-ORGANIC FRAMEWORKS | UNIV NOTTINGHAM (GB) | 2015-06-25 | — | — | US | disclosed |
| WO-2014013274-A2 | METAL-ORGANIC FRAMEWORKS | THE UNIVERSITY OF NOTTINGHAM (GB) | 2014-01-23 | — | — | WO | disclosed |
| US-8163949-B2 | Method for electrochemical production of a crystalline porous metal organic skeleton material | BASF AKTIENGESELLSCHAFT (DE) | 2012-04-24 | — | — | US | disclosed |
| US-7968739-B2 | Method for electrochemical production of a crystalline porous metal organic skeleton material | BASF AKTIENGESELLSCHAFT (DE) | 2011-06-28 | — | — | US | disclosed |
| US-20110105776-A1 | METHOD FOR ELECTROCHEMICAL PRODUCTION OF A CRYSTALLINE POROUS METAL ORGANIC SKELETON MATERIAL | BASF AKTIENGESELLSCHAFT (DE) | 2011-05-05 | — | — | US | disclosed |
| US-20070227898-A1 | Method for Electrochemical Production of a Crystalline Porous Metal Organic Skeleton Material | BASF AKTIENGESELLSCHAFT (DE) | 2007-10-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150175518-A1 | METAL-ORGANIC FRAMEWORKS | TRPM4, TRPM8, TRPM6 | AKR1C3 3215/4885KDM4E 3607/4885HSD17B10 3965/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.