SCHEMBL1801932

SCHEMBL1801932

C=Cc1ccc(Nc2ccc(O)c3c2C(=O)c2ccccc2C3=O)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.63
KMT2A Q03164 5/20 0.63
MAPT P10636 5/20 0.63
MAPK1 P28482 4/20 0.63
TDP1 Q9NUW8 3/20 0.63
LMNA P02545 2/20 0.63
L3MBTL1 Q9Y468 2/20 0.63
NPC1 O15118 1/20 0.63
RAB9A P51151 1/20 0.63
NPSR1 Q6W5P4 1/20 0.63
PRKCA P17252 2/20 0.56
MAOA P21397 3/20 0.51
HPGD P15428 3/20 0.48
POLB P06746 2/20 0.48
MCL1 Q07820 2/20 0.48
SMN1; SMN2 Q16637 2/20 0.48
PABPC1 P11940 1/20 0.48
CSNK1A1 P48729 1/20 0.48
CSNK1D P48730 1/20 0.48
BLM P54132 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1800594 0.92 LMNA (0.50) MEN1KMT2AMAPTMAPK1TDP1
SCHEMBL13797748 0.88 MEN1 (0.64) MEN1KMT2AMAPTMAPK1TDP1
SCHEMBL1803680 0.85 P2RY2 (0.51) MEN1KMT2AMAPTMAPK1TDP1
SCHEMBL5273789 0.84 MAPT (0.71) MEN1KMT2AMAPTMAPK1TDP1
SCHEMBL29500408 0.84 MEN1 (0.70) MEN1KMT2AMAPTMAPK1TDP1
SCHEMBL341146 0.84 MEN1 (0.70) MEN1KMT2AMAPTMAPK1TDP1
SCHEMBL14403132 0.82 MEN1 (0.64) MEN1KMT2AMAPTMAPK1TDP1
Formaldehyde SCHEMBL27614219 0.82 MAPT (0.64) MEN1KMT2AMAPTMAPK1TDP1
SCHEMBL29353964 0.82 MAPT (0.67) MEN1KMT2AMAPTMAPK1TDP1
SCHEMBL30850671 0.82 MEN1 (0.67) MEN1KMT2AMAPTMAPK1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2330161-B1 DYE COMPOSITION FOR OPHTHALMIC LENS, METHOD FOR PRODUCING COLORED OPHTHALMIC LENS USING THE SAME AND COLORED OPHTHALMIC LENS MENICON CO LTD (JP) 2017-01-25 EP disclosed
US-8927618-B2 Dye composition for ophthalmic lens, method for producing colored ophthalmic lens using the same, and colored ophthalmic lens MENICON CO., LTD. (JP) 2015-01-06 US disclosed
EP-2514791-A1 ANTHRAQUINONE PIGMENT, OCULAR LENS MATERIAL USING SAME, OCULAR LENS MATERIAL MANUFACTURING METHOD, AND OCULAR LENS Menicon Co., Ltd. (JP) 2012-10-24 EP disclosed
EP-2330161-A1 Dye composition for ophthalmic lens, method for producing colored ophthalmic lens using the same, and colored ophthalmic lens Menicon Co., Ltd. (JP) 2011-06-08 EP disclosed
US-20110116034-A1 Dye composition for ophthalmic lens, method for producing colored ophthalmic lens using the same, and colored ophthalmic lens MENICON CO., LTD. (JP) 2011-05-19 US disclosed