Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.32 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17977359 | 0.81 | MYC (0.37) | ESR2CHRNA7ESR1 | |
| SCHEMBL18019397 | 0.79 | ADH5 (0.40) | — | |
| SCHEMBL17977333 | 0.74 | CHRNA7 (0.33) | ESR2CHRNA7ESR1 | |
| SCHEMBL17977349 | 0.71 | MYC (0.34) | ESR2CHRNA7ESR1 | |
| SCHEMBL17977408 | 0.70 | PDE4A (0.38) | F2 | |
| SCHEMBL17977419 | 0.70 | ADH5 (0.46) | — | |
| SCHEMBL17977471 | 0.70 | MYC (0.34) | — | |
| SCHEMBL17977388 | 0.69 | PDE4A (0.37) | F2 | |
| SCHEMBL18019402 | 0.69 | ADH5 (0.39) | — | |
| SCHEMBL17977477 | 0.69 | STING1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016128905-A1 | THIENOPYRROLE COMPOUNDS AS S-NITROSOGLUTATHIONE REDUCTASE INHIBITORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2016-08-18 | — | — | WO | disclosed |