Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 4/20 | 0.68 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.68 |
| ▸ | PPARG | P37231 | 1/20 | 0.68 |
| ▸ | PPARD | Q03181 | 1/20 | 0.68 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.60 |
| ▸ | PLA2G4B | P0C869 | 3/20 | 0.58 |
| ▸ | ALB | P02768 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.54 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.54 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.54 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4298103 | 1.00 | PPARA (0.68) | PPARAFFAR1PPARGPPARDPDE4B | |
| SCHEMBL8483507 | 1.00 | PPARA (0.68) | PPARAFFAR1PPARGPPARDPDE4B | |
| SCHEMBL15176983 | 0.98 | PPARA (0.65) | PPARAFFAR1PPARGPPARDPDE4B | |
| SCHEMBL8029095 | 0.93 | PDE4B (0.64) | PPARAFFAR1PPARGPPARDPDE4B | |
| Hydrochloric Acid SCHEMBL8981950 | 0.91 | PDE4B (0.62) | PPARAFFAR1PPARGPPARDPDE4B | |
| SCHEMBL31448424 | 0.91 | PPARA (0.71) | PPARAFFAR1PLA2G4BALBL3MBTL1 | |
| SCHEMBL29141429 | 0.91 | PPARA (0.71) | PPARAFFAR1PLA2G4BALBL3MBTL1 | |
| SCHEMBL21073528 | 0.91 | PPARA (0.71) | PPARAFFAR1PLA2G4BALBL3MBTL1 | |
| SCHEMBL6438671 | 0.89 | PPARA (0.57) | PPARAFFAR1PPARGPPARDPDE4B | |
| SCHEMBL31448470 | 0.89 | PPARA (0.73) | PPARAFFAR1PLA2G4BALBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8410309-B2 | Phenoxy carboxylic acid compounds and compositions for delivering active agents | EMISPHERE TECHNOLOGIES, INC. (US) | 2013-04-02 | — | — | US | disclosed |
| US-7951971-B1 | Phenoxy carboxylic acid compounds and compositions for delivering active agents | EMISPHERE TECHNOLOGIES, INC. (US) | 2011-05-31 | — | — | US | disclosed |
| EP-1226104-B1 | PHENOXY CARBOXYLIC ACID COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | EMISPHERE TECH INC (US) | 2009-04-08 | — | — | EP | disclosed |
| US-20060264513-A1 | PHENOXY CARBOXYLIC ACID COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | EMISPHERE TECHNOLOGIES, INC. (US) | 2006-11-23 | — | — | US | disclosed |
| US-7129274-B1 | Phenoxy carboxylic acid compounds and compositions for delivering active agents | EMISPHERE TECHNOLOGIES INC. (US) | 2006-10-31 | — | — | US | disclosed |
| EP-1226104-A1 | PHENOXY CARBOXYLIC ACID COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | Emisphere Technologies, Inc. (US) | 2002-07-31 | — | — | EP | disclosed |
| WO-2001032596-A1 | PHENOXY CARBOXYLIC ACID COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | EMISPHERE TECHNOLOGIES, INC. (US) | 2001-05-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060264513-A1 | PHENOXY CARBOXYLIC ACID COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | SLC46A1, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, PAICS | PPARA 162/4885FFAR1 781/4885PPARG 103/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.