Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 1/20 | 0.64 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.61 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | PPARA | Q07869 | 3/20 | 0.58 |
| ▸ | PPARG | P37231 | 1/20 | 0.58 |
| ▸ | PPARD | Q03181 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.54 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8981950 | 0.98 | PDE4B (0.62) | PDE4BFFAR1FFAR4MAPTL3MBTL1 | |
| SCHEMBL15176983 | 0.94 | PPARA (0.65) | PDE4BFFAR1FFAR4MAPTL3MBTL1 | |
| Mequinol SCHEMBL10533614 | 0.93 | PDE4B (0.57) | PDE4BFFAR1FFAR4MAPTL3MBTL1 | |
| SCHEMBL4298103 | 0.93 | PPARA (0.68) | PDE4BFFAR1FFAR4MAPTL3MBTL1 | |
| SCHEMBL1801957 | 0.93 | PPARA (0.68) | PDE4BFFAR1FFAR4MAPTL3MBTL1 | |
| SCHEMBL8483507 | 0.93 | PPARA (0.68) | PDE4BFFAR1FFAR4MAPTL3MBTL1 | |
| SCHEMBL9730131 | 0.92 | PPARA (0.69) | PDE4BFFAR1FFAR4MAPTL3MBTL1 | |
| SCHEMBL1807043 | 0.90 | L3MBTL1 (0.72) | PDE4BFFAR1MAPTL3MBTL1PPARA | |
| SCHEMBL12311085 | 0.90 | PDE4B (0.54) | PDE4BFFAR1FFAR4MAPTL3MBTL1 | |
| SCHEMBL31448501 | 0.90 | PPARA (0.65) | FFAR1FFAR4L3MBTL1PPARAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6166031-A | Substituted tetralins, chromans and related compounds in the treatment of asthma | PFIZER INC, (US) | 2000-12-26 | — | — | US | disclosed |
| US-5998451-A | LIPOXYGENASE INHIBITORS | PFIZER INC (US) | 1999-12-07 | — | — | US | disclosed |
| US-5990158-A | EXTRACELLULAR MATRIX METALLOPROTEINASES INHIBITORS; ORAL ADMINISTRATION; BIOAVAILABILITY; E.G.,N-(2-(2'-(5-METHYL-2-OXO-1,3-DIOXOL-4-YL)METHYLENE-OXY-2'-OXO-ETHYL)-5 -(4-METH-OXYPHENYL)OXY)PENTANOYL)PHENYLALANINE N-METHYLAMIDE | KOTOBUKI SEIYAKU CO., LTD. (JP) | 1999-11-23 | — | — | US | disclosed |
| EP-0487343-B1 | Process for preparing a lithographic plate | FUJI PHOTO FILM CO LTD (JP) | 1999-04-28 | — | — | EP | disclosed |
| EP-0423796-B1 | Thermal transfer dye donating materials | FUJI PHOTO FILM CO LTD (JP) | 1996-05-29 | — | — | EP | disclosed |
| US-5403811-A | Colorfast images | FUJI PHOTO FILM CO., LTD. (JP) | 1995-04-04 | — | — | US | disclosed |
| US-5262377-A | Colorfastness | FUJI PHOTO FILM CO., LTD. (JP) | 1993-11-16 | — | — | US | disclosed |
| CN-1021823-C | Substituted chroman compounds for treatment of asthma, arthritis and the like | PFIZER (US) | 1993-08-18 | — | — | CN | disclosed |
| EP-0313295-B1 | SUBSTITUTED TETRALINS, CHROMANS AND RELATED COMPOUNDS IN THE TREATMENT OF ASTHMA, ARTHRITIS AND RELATED DISEASES | PFIZER INC. (US) | 1993-07-28 | — | — | EP | disclosed |
| CN-1064864-A | The tetraline that replaces and the preparation method of allied compound | PFIZER (US) | 1992-09-30 | — | — | CN | disclosed |
| CN-1063489-A | Substituted benzotetrahydropyridines and related compounds | PFIZER (US) | 1992-08-12 | — | — | CN | disclosed |
| EP-0487343-A1 | Process for preparing a lithographic plate | Fuji Photo Film Co., Ltd. (JP) | 1992-05-27 | — | — | EP | disclosed |
| US-5059609-A | Lipoxygenase inhibitors; leukotriene receptor blockers; psoriasis; antiulcer agents and myocardial infarctions | PFIZER INC. (US) | 1991-10-22 | — | — | US | disclosed |
| CN-1032659-A | Substituted tetralins, chromans and like compounds for the treatment of asthma, arthritis and like diseases | PFIZER (US) | 1989-05-03 | — | — | CN | disclosed |
| EP-0313295-A2 | Substituted tetralins, chromans and related compounds in the treatment of asthma, arthritis and related diseases | PFIZER INC. (US) | 1989-04-26 | — | — | EP | disclosed |
| EP-0313296-A2 | Substituted chromans and related compounds in the treatment of asthma | PFIZER INC. (US) | 1989-04-26 | — | — | EP | disclosed |