Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | PGR | P06401 | 4/20 | 0.47 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.44 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18019946 | 0.97 | KMT2A (0.43) | KDM4EL3MBTL1ATMKMT2APGR | |
| SCHEMBL18019940 | 0.92 | ATM (0.47) | KDM4EL3MBTL1ATMKMT2APGR | |
| SCHEMBL18019942 | 0.90 | KDM4E (0.58) | KDM4EL3MBTL1ATMKMT2APGR | |
| SCHEMBL18020166 | 0.90 | PGR (0.48) | KDM4EL3MBTL1ATMKMT2APGR | |
| SCHEMBL14933364 | 0.89 | KMT2A (0.52) | KDM4EL3MBTL1ATMKMT2APGR | |
| SCHEMBL18020167 | 0.89 | PGR (0.47) | KDM4EL3MBTL1ATMKMT2APGR | |
| SCHEMBL15988942 | 0.87 | L3MBTL1 (0.62) | KDM4EL3MBTL1ATMKMT2APGR | |
| SCHEMBL19844355 | 0.86 | PGR (0.51) | KDM4EL3MBTL1ATMKMT2APGR | |
| SCHEMBL17019445 | 0.86 | L3MBTL1 (0.60) | KDM4EL3MBTL1ATMKMT2APGR | |
| SCHEMBL18019987 | 0.85 | KDM4E (0.49) | KDM4EL3MBTL1ATMKMT2APGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10249831-B2 | Electronic device containing cyclic lactams | MERCK PATENT GMBH (DE) | 2019-04-02 | — | — | US | disclosed |
| US-20180040832-A1 | ELECTRONIC DEVICE CONTAINING CYCLIC LACTAMS | MERCK PATENT GMBH (DE) | 2018-02-08 | — | — | US | disclosed |
| US-20180040832-A1 | ELECTRONIC DEVICE CONTAINING CYCLIC LACTAMS | MERCK PATENT GMBH (DE) | 2018-02-08 | — | — | US | disclosed |
| WO-2016128103-A1 | ELECTRONIC DEVICE CONTAINING CYCLIC LACTAMS | MERCK PATENT GMBH (DE) | 2016-08-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10249831-B2 | Electronic device containing cyclic lactams | OXA1L, UROD, MRPL21 | KDM4E 2116/4885L3MBTL1 3138/4885ATM 3206/4885 |
| US-20180040832-A1 | ELECTRONIC DEVICE CONTAINING CYCLIC LACTAMS | OXA1L, UROD, MRPL21 | KDM4E 2116/4885L3MBTL1 3138/4885ATM 3206/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.