Mianserin

Mianserin

SCHEMBL18020

CN1CCN2c3ccccc3Cc3ccccc3C2C1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DRD3 P35462 8/20 1.00
HTR2A P28223 7/20 1.00
DRD2 P14416 7/20 1.00
HTR1A P08908 6/20 1.00
HTR2C P28335 5/20 1.00
HTR2B P41595 5/20 1.00
DRD4 P21917 4/20 1.00
HTR1D P28221 3/20 1.00
ADRA2A P08913 3/20 1.00
DRD1 P21728 3/20 1.00
ADRA1A P35348 3/20 1.00
LMNA P02545 2/20 1.00
MEN1 O00255 2/20 1.00
TP53 P04637 2/20 1.00
CYP3A4 P08684 2/20 1.00
KMT2A Q03164 2/20 1.00
CYP1A2 P05177 2/20 1.00
CYP2D6 P10635 2/20 1.00
CYP2C9 P11712 2/20 1.00
TSHR P16473 2/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Mianserin SCHEMBL9122085 1.00 DRD3 (1.00) DRD3HTR2ADRD2HTR1AHTR2C
Mianserin SCHEMBL29356897 1.00 DRD3 (1.00) DRD3HTR2ADRD2HTR1AHTR2C
Mianserin SCHEMBL23326358 1.00 DRD3 (1.00) DRD3HTR2ADRD2HTR1AHTR2C
Mianserin SCHEMBL353397 1.00 DRD3 (1.00) DRD3HTR2ADRD2HTR1AHTR2C
Mianserin SCHEMBL9752060 0.98 DRD3 (0.97) DRD3HTR2ADRD2HTR1AHTR2C
Mianserin SCHEMBL8344416 0.98 DRD3 (0.97) DRD3HTR2ADRD2HTR1AHTR2C
Mianserin SCHEMBL11336834 0.98 HTR2A (0.97) DRD3HTR2ADRD2HTR1AHTR2C
Mianserin SCHEMBL340474 0.98 MEN1 (1.00) DRD3HTR2ADRD2HTR1AHTR2C
Mianserin SCHEMBL29366576 0.98 MEN1 (1.00) DRD3HTR2ADRD2HTR1AHTR2C
Mianserin SCHEMBL2571368 0.97 DRD3 (0.94) DRD3HTR2ADRD2HTR1AHTR2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 15874 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260108493-A1 COMPOSITIONS COMPRISING A SEROTONERGIC TRYPTAMINE COMPOUND CAAMTECH, INC. (US) 2026-04-23 US claimed
EP-4704971-A1 GAMMA STIMULATION AND NEUROMODULATOR COMBINATION THERAPY Cognito Therapeutics, Inc. (US) 2026-03-11 EP claimed
EP-4706649-A1 USE OF ADRENALIN FOR THE TREATMENT OF SHOCKS BIOPROJET (FR) 2026-03-11 EP claimed
US-12544385-B2 Combination drug therapies for CNS disorders JAVED MOHAMMAD (US) 2026-02-10 US claimed
US-20260034065-A1 EXTENDED RELEASE PHARMACEUTICAL FORMULATION DOUGLAS PHARMACEUTICALS LTD (NZ) 2026-02-05 US claimed
EP-3507371-B1 COMPOSITIONS FOR TREATING DISEASES AND DISORDERS OF THE NERVOUS SYSTEM UNIV RUTGERS (US) 2026-01-28 EP claimed
US-20260001942-A1 TREATMENT OF HEADACHE DISORDERS AND/OR PSYCHIATRIC SYMPTOMS USING ANTI-CGRP ANTIBODIES, AND COMPOSITIONS AND METHODS RELATED THERETO H LUNDBECK AS (DK) 2026-01-01 US claimed
US-20260000641-A1 ISOTOPICALLY ENRICHED ANALOGS OF 5,6-METHYLENEDIOXY-2-AMINOINDANE (IMDAI) TERRAN BIOSCIENCES INC (US) 2026-01-01 US claimed
WO-2025262247-A1 TREATMENT OF HEADACHE DISORDERS AND/OR PSYCHIATRIC SYMPTOMS USING ANTI-CGRP ANTIBODIES, AND COMPOSITIONS AND METHODS RELATED THERETO H. LUNDBECK A/S (DK) 2025-12-26 WO claimed
WO-2025264604-A1 SKIN CARE COMPOSITION AND METHOD OF USING THE SAME THE PROCTER & GAMBLE COMPANY (US) 2025-12-26 WO claimed
US-4956361-A DICARBOXYLIC ACID ESTERS OF DIHYDROPYRIDINES TROPONWERKE GMBH & CO. KG (DE) 1990-09-11 US claimed
EP-0322795-A2 Novel tetrapyrrole aminocarboxylic acids Nippon Petrochemicals Co., Ltd. (JP) 1989-07-05 EP claimed
EP-0293714-A1 Combinations of compounds with anti-depressive activity Troponwerke GmbH & Co. KG (DE) 1988-12-07 EP claimed
EP-0181800-B1 PROCESS FOR SWEETENING HYDROCARBON FRACTIONS IN THE ABSENCE OF AN ALKALI COMPOUND Institut Français du Pétrole (FR) 1988-04-27 EP claimed
US-4675338-A PEPTIDE LINKAGES WITH ASPARTIC AND GLUTAMIC ACID; ANTITUMOR A GENTS NIPPON PETROCHEMICALS CO., LTD. (JP) 1987-06-23 US claimed
EP-0181800-A1 Process for sweetening hydrocarbon fractions in the absence of an alkali compound Institut Français du Pétrole (FR) 1986-05-21 EP claimed
EP-0089948-B1 PHARMACEUTICAL COMPOSITIONS COPPEN, Alec James (GB) 1985-08-14 EP claimed
US-4444778-A ANTISEROTONINE AGENTS COUGHLIN SHAUN R 1984-04-24 US claimed
US-4310524-A TCA Composition and method for rapid onset antidepressant therapy RICHARDSON-MERRELL, INC. (US) 1982-01-12 US claimed
US-4171309-A Process for the preparation of a solvent-stable, red-shade copper phthalocyanine pigment composition CIBA-GEIGY CORPORATION (US) 1979-10-16 US claimed