Mianserin

Mianserin

SCHEMBL9752060

CN1CCN2c3ccccc3Cc3ccccc3C2C1.[SiH4]

nearest known ligand 0.97

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DRD3 P35462 8/20 0.97
HTR2A P28223 7/20 0.97
DRD2 P14416 7/20 0.97
HTR1A P08908 6/20 0.97
HTR2C P28335 5/20 0.97
HTR2B P41595 5/20 0.97
DRD4 P21917 4/20 0.97
HTR1D P28221 3/20 0.97
ADRA2A P08913 3/20 0.97
DRD1 P21728 3/20 0.97
ADRA1A P35348 3/20 0.97
LMNA P02545 2/20 0.97
MEN1 O00255 2/20 0.97
TP53 P04637 2/20 0.97
CYP3A4 P08684 2/20 0.97
KMT2A Q03164 2/20 0.97
CYP1A2 P05177 2/20 0.97
CYP2D6 P10635 2/20 0.97
CYP2C9 P11712 2/20 0.97
TSHR P16473 2/20 0.97

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Mianserin SCHEMBL23326358 0.98 DRD3 (1.00) DRD3HTR2ADRD2HTR1AHTR2C
Mianserin SCHEMBL18020 0.98 DRD3 (1.00) DRD3HTR2ADRD2HTR1AHTR2C
Mianserin SCHEMBL353397 0.98 DRD3 (1.00) DRD3HTR2ADRD2HTR1AHTR2C
Mianserin SCHEMBL29356897 0.98 DRD3 (1.00) DRD3HTR2ADRD2HTR1AHTR2C
Mianserin SCHEMBL9122085 0.98 DRD3 (1.00) DRD3HTR2ADRD2HTR1AHTR2C
Mianserin SCHEMBL8344416 0.97 DRD3 (0.97) DRD3HTR2ADRD2HTR1AHTR2C
Mianserin SCHEMBL11336834 0.97 HTR2A (0.97) DRD3HTR2ADRD2HTR1AHTR2C
Mianserin SCHEMBL340474 0.97 MEN1 (1.00) DRD3HTR2ADRD2HTR1AHTR2C
Mianserin SCHEMBL29366576 0.97 MEN1 (1.00) DRD3HTR2ADRD2HTR1AHTR2C
Mianserin SCHEMBL340475 0.96 DRD3 (0.94) DRD3HTR2ADRD2HTR1AHTR2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-3016903-A None JP disclosed
US-10384941-B2 Method for producing spherical silicon nitride powder NATIONAL CHUNG SHAN INSTITUTE OF SCIENCE AND TECHNOLOGY (TW) 2019-08-20 US disclosed
US-20190177162-A1 METHOD FOR PRODUCING SPHERICAL SILICON NITRIDE POWDER NATIONAL CHUNG SHAN INSTITUTE OF SCIENCE AND TECHNOLOGY (TW) 2019-06-13 US disclosed
EP-2660202-B1 POLYCRYSTALLINE SILICON INGOT CASTING MOLD, AND SILICON NITRIDE POWDER FOR MOLD RELEASE MATERIAL, SLURRY CONTAINING SILICON NITRIDE POWDER FOR MOLD RELEASE LAYER AND CASTING RELEASE MATERIAL THEREFOR UBE INDUSTRIES (JP) 2016-12-28 EP disclosed
US-8864481-B2 Mold for casting polycrystalline silicon ingot, and silicon nitride powder for mold release material thereof, slurry containing silicon nitride powder for mold release layer thereof and mold release material for casting thereof UBE INDUSTRIES, LTD. (JP) 2014-10-21 US disclosed
EP-2660202-A1 POLYCRYSTALLINE SILICON INGOT CASTING MOLD, AND SILICON NITRIDE POWDER FOR MOLD RELEASE MATERIAL, SLURRY CONTAINING SILICON NITRIDE POWDER FOR MOLD RELEASE LAYER AND CASTING RELEASE MATERIAL THEREFOR Ube Industries, Ltd. (JP) 2013-11-06 EP disclosed
US-20130273189-A1 Mold for Casting Polycrystalline Silicon Ingot, and Silicon Nitride Powder for Mold Release Material Thereof, Slurry Containing Silicon Nitride Powder for Mold Release Layer Thereof and Mold Release Material for Casting Thereof UBE INDUSTRIES, LTD. (JP) 2013-10-17 US disclosed
JP-H0316903-A PRODUCTION OF CRYSTALLINE SILICON NITRIDE POWDER UBE IND LTD 1991-01-24 JP disclosed
EP-0217633-B1 METHOD FOR PRODUCING SIALON POWDERS UBE INDUSTRIES, LTD. (JP) 1990-01-31 EP disclosed
US-4812298-A HEATING SILICON NITRIDE, SILICA AND-OR ALUMINA, ALUMINUM, ALUMINUM NITRIDE AND-OR SILICON UBE INDUSTRIES, LTD. (JP) 1989-03-14 US disclosed
EP-0251522-A2 Process for production of beta-type silicon nitride UBE INDUSTRIES, LTD. (JP) 1988-01-07 EP disclosed
EP-0217633-A1 Method for producing sialon powders UBE INDUSTRIES, LTD. (JP) 1987-04-08 EP disclosed
US-4405589-A ALKYL OR ARYL SILICON CHLORIDES, AMMONIA, ROASTING UBE INDUSTRIES, LTD. (JP) 1983-09-20 US disclosed