Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 8/20 | 0.97 |
| ▸ | DRD3 | P35462 | 8/20 | 0.97 |
| ▸ | HTR2C | P28335 | 6/20 | 0.97 |
| ▸ | HTR2B | P41595 | 6/20 | 0.97 |
| ▸ | HTR1A | P08908 | 6/20 | 0.97 |
| ▸ | DRD2 | P14416 | 6/20 | 0.97 |
| ▸ | DRD4 | P21917 | 4/20 | 0.97 |
| ▸ | HTR1D | P28221 | 3/20 | 0.97 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.97 |
| ▸ | DRD1 | P21728 | 3/20 | 0.97 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.97 |
| ▸ | LMNA | P02545 | 2/20 | 0.97 |
| ▸ | MEN1 | O00255 | 2/20 | 0.97 |
| ▸ | TP53 | P04637 | 2/20 | 0.97 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.97 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.97 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.97 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.97 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.97 |
| ▸ | TSHR | P16473 | 2/20 | 0.97 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Mianserin SCHEMBL23326358 | 0.98 | DRD3 (1.00) | HTR2ADRD3HTR2CHTR2BHTR1A | |
| Mianserin SCHEMBL18020 | 0.98 | DRD3 (1.00) | HTR2ADRD3HTR2CHTR2BHTR1A | |
| Mianserin SCHEMBL29356897 | 0.98 | DRD3 (1.00) | HTR2ADRD3HTR2CHTR2BHTR1A | |
| Mianserin SCHEMBL9122085 | 0.98 | DRD3 (1.00) | HTR2ADRD3HTR2CHTR2BHTR1A | |
| Mianserin SCHEMBL353397 | 0.98 | DRD3 (1.00) | HTR2ADRD3HTR2CHTR2BHTR1A | |
| Mianserin SCHEMBL340474 | 0.97 | MEN1 (1.00) | HTR2ADRD3HTR2CHTR2BHTR1A | |
| Mianserin SCHEMBL9752060 | 0.97 | DRD3 (0.97) | HTR2ADRD3HTR2CHTR2BHTR1A | |
| Mianserin SCHEMBL8344416 | 0.97 | DRD3 (0.97) | HTR2ADRD3HTR2CHTR2BHTR1A | |
| Mianserin SCHEMBL29366576 | 0.97 | MEN1 (1.00) | HTR2ADRD3HTR2CHTR2BHTR1A | |
| Mianserin SCHEMBL2571368 | 0.96 | DRD3 (0.94) | HTR2ADRD3HTR2CHTR2BHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4268491-A | IODINE, SEMICONDUCTORS | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1981-05-19 | — | — | US | disclosed |