Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | PARP1 | P09874 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.47 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | PAK4 | O96013 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.41 |
| ▸ | CSF1R | P07333 | 1/20 | 0.41 |
| ▸ | RET | P07949 | 1/20 | 0.41 |
| ▸ | MET | P08581 | 1/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17979420 | 0.85 | CA12 (0.49) | CA12CA9PARP1KDM4EPDE3A | |
| SCHEMBL8900615 | 0.83 | PDE3A (0.62) | CA12CA9PARP1KDM4EPDE3A | |
| SCHEMBL182445 | 0.81 | JAK2 (0.60) | CA12CA9PARP1KDM4ECHEK1 | |
| SCHEMBL18020134 | 0.81 | PDE3A (0.59) | CA12CA9PARP1KDM4EPDE3A | |
| SCHEMBL18020129 | 0.79 | PARP1 (0.61) | CA12CA9PARP1KDM4EPDE3A | |
| SCHEMBL18020131 | 0.77 | PDE3A (0.49) | CA12CA9PARP1KDM4EPDE3A | |
| SCHEMBL19844373 | 0.76 | ALDH1A1 (0.51) | CA12CA9PARP1KDM4EPDE3A | |
| SCHEMBL19850400 | 0.76 | PDE3A (0.51) | CA12CA9PARP1KDM4EPDE3A | |
| SCHEMBL31441277 | 0.76 | CA12 (0.49) | CA12CA9PARP1KDM4EPDE3A | |
| SCHEMBL16305032 | 0.76 | IDO1 (0.55) | KDM4EIDO1TDO2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3257093-B1 | ELECTRONIC DEVICE CONTAINING CYCLIC LACTAMS | MERCK PATENT GMBH (DE) | 2021-07-07 | — | — | EP | disclosed |
| US-10249831-B2 | Electronic device containing cyclic lactams | MERCK PATENT GMBH (DE) | 2019-04-02 | — | — | US | disclosed |
| US-20180040832-A1 | ELECTRONIC DEVICE CONTAINING CYCLIC LACTAMS | MERCK PATENT GMBH (DE) | 2018-02-08 | — | — | US | disclosed |
| US-20180040832-A1 | ELECTRONIC DEVICE CONTAINING CYCLIC LACTAMS | MERCK PATENT GMBH (DE) | 2018-02-08 | — | — | US | disclosed |
| WO-2016128103-A1 | ELECTRONIC DEVICE CONTAINING CYCLIC LACTAMS | MERCK PATENT GMBH (DE) | 2016-08-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10249831-B2 | Electronic device containing cyclic lactams | OXA1L, UROD, MRPL21 | CA12 1575/4885CA9 1764/4885PARP1 2150/4885 |
| US-20180040832-A1 | ELECTRONIC DEVICE CONTAINING CYCLIC LACTAMS | OXA1L, UROD, MRPL21 | CA12 1575/4885CA9 1764/4885PARP1 2150/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.